Oncocytic carcinoma of the submandibular gland: A case report and literature review

Michihiro Nakada, Kazunori Nishizaki, Hirofumi Akagi, Yu Masuda, Tadashi Yoshino

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Oncocytes are characterized by a remarkable number of mitochondria as demonstrated by electron microscopy. Oncocytomas are very rare tumors that are usually benign and typically occur in the parotid gland. Oncocytic carcinomas are exceedingly rare in the salivary glands. We describe a 69-year-old Japanese man with an oncocytic carcinoma of the submandibular gland. We reviewed 38 articles describing oncocytic carcinoma of the head and neck that included clinicopathologic features. Oncocytic carcinomas appear to arise from benign oncocytomas, or may also arise de novo. In oncocytic carcinoma of the head and neck, the presence of distant, rather than local lymph node, metastasis is the most important prognostic indicator.

Original languageEnglish
Pages (from-to)225-228
Number of pages4
JournalJournal of Oral Pathology and Medicine
Volume27
Issue number5
Publication statusPublished - May 1998

Fingerprint

Submandibular Gland
Carcinoma
Oxyphilic Adenoma
Neck
Head
Oxyphil Cells
Parotid Gland
Salivary Glands
Electron Microscopy
Mitochondria
Lymph Nodes
Neoplasm Metastasis
Neoplasms

Keywords

  • Mitochondria
  • Oncocyte
  • Oncocytic carcinoma
  • Oncocytoma
  • Submandibular gland

ASJC Scopus subject areas

  • Cancer Research
  • Pathology and Forensic Medicine
  • Dentistry(all)

Cite this

Oncocytic carcinoma of the submandibular gland : A case report and literature review. / Nakada, Michihiro; Nishizaki, Kazunori; Akagi, Hirofumi; Masuda, Yu; Yoshino, Tadashi.

In: Journal of Oral Pathology and Medicine, Vol. 27, No. 5, 05.1998, p. 225-228.

Research output: Contribution to journalArticle

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