On detailed contrast of biomedical object in X-ray dark-field imaging

Daisuke Shimao, Hiroshi Sugiyama, Toshiyuki Kunisada, Kazuyuki Hyodo, Koichi Mori, Masami Ando

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Over the past 10 years, refraction-based X-ray imaging has been studied together with a perspective view to clinical application. X-ray Dark-Field Imaging that utilizes a Laue geometry analyzer has recently been proposed and has the proven ability to depict articular cartilage in an intact human finger. In the current study, we researched detailed image contrast using X-ray Dark-Field Imaging by observing the edge contrast of an acrylic rod as a simple case, and found differences in image contrast between the right and left edges of the rod. This effect could cause undesirable contrast in the thin articular cartilage on the head of the phalanx. To avoid overlapping with this contrast at the articular cartilage, which would lead to a wrong diagnosis, we suggest that a joint surface on which articular cartilage is located should be aligned in the same sense as the scattering vector of the Laue case analyzer crystal. Defects of articular cartilage were successfully detected under this condition. When utilized under appropriate imaging conditions, X-ray Dark-Field Imaging will be a powerful tool for the diagnosis of arthropathy, as minute changes in articular cartilage may be early-stage features of this disease.

Original languageEnglish
Title of host publicationAIP Conference Proceedings
Pages1960-1963
Number of pages4
Volume879
DOIs
Publication statusPublished - 2007
EventSYNCHROTRON RADIATION INSTRUMENTATION: 9th International Conference on Synchrotron Radiation Instrumentation - Daegu, Korea, Republic of
Duration: May 28 2006Jun 28 2006

Other

OtherSYNCHROTRON RADIATION INSTRUMENTATION: 9th International Conference on Synchrotron Radiation Instrumentation
CountryKorea, Republic of
CityDaegu
Period5/28/066/28/06

Fingerprint

cartilage
x rays
image contrast
analyzers
rods
refraction
causes
defects
geometry
scattering
crystals

Keywords

  • Articular cartilage
  • Object direction
  • Refraction contrast
  • X-ray dark-field imaging

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Shimao, D., Sugiyama, H., Kunisada, T., Hyodo, K., Mori, K., & Ando, M. (2007). On detailed contrast of biomedical object in X-ray dark-field imaging. In AIP Conference Proceedings (Vol. 879, pp. 1960-1963) https://doi.org/10.1063/1.2436458

On detailed contrast of biomedical object in X-ray dark-field imaging. / Shimao, Daisuke; Sugiyama, Hiroshi; Kunisada, Toshiyuki; Hyodo, Kazuyuki; Mori, Koichi; Ando, Masami.

AIP Conference Proceedings. Vol. 879 2007. p. 1960-1963.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shimao, D, Sugiyama, H, Kunisada, T, Hyodo, K, Mori, K & Ando, M 2007, On detailed contrast of biomedical object in X-ray dark-field imaging. in AIP Conference Proceedings. vol. 879, pp. 1960-1963, SYNCHROTRON RADIATION INSTRUMENTATION: 9th International Conference on Synchrotron Radiation Instrumentation, Daegu, Korea, Republic of, 5/28/06. https://doi.org/10.1063/1.2436458
Shimao D, Sugiyama H, Kunisada T, Hyodo K, Mori K, Ando M. On detailed contrast of biomedical object in X-ray dark-field imaging. In AIP Conference Proceedings. Vol. 879. 2007. p. 1960-1963 https://doi.org/10.1063/1.2436458
Shimao, Daisuke ; Sugiyama, Hiroshi ; Kunisada, Toshiyuki ; Hyodo, Kazuyuki ; Mori, Koichi ; Ando, Masami. / On detailed contrast of biomedical object in X-ray dark-field imaging. AIP Conference Proceedings. Vol. 879 2007. pp. 1960-1963
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