On detailed contrast of biomedical object in X-ray dark-field imaging

Daisuke Shimao, Hiroshi Sugiyama, Toshiyuki Kunisada, Kazuyuki Hyodo, Koichi Mori, Masami Ando

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Over the past 10 years, refraction-based X-ray imaging has been studied together with a perspective view to clinical application. X-ray Dark-Field Imaging that utilizes a Laue geometry analyzer has recently been proposed and has the proven ability to depict articular cartilage in an intact human finger. In the current study, we researched detailed image contrast using X-ray Dark-Field Imaging by observing the edge contrast of an acrylic rod as a simple case, and found differences in image contrast between the right and left edges of the rod. This effect could cause undesirable contrast in the thin articular cartilage on the head of the phalanx. To avoid overlapping with this contrast at the articular cartilage, which would lead to a wrong diagnosis, we suggest that a joint surface on which articular cartilage is located should be aligned in the same sense as the scattering vector of the Laue case analyzer crystal. Defects of articular cartilage were successfully detected under this condition. When utilized under appropriate imaging conditions, X-ray Dark-Field Imaging will be a powerful tool for the diagnosis of arthropathy, as minute changes in articular cartilage may be early-stage features of this disease.

Original languageEnglish
Title of host publicationSYNCHROTRON RADIATION INSTRUMENTATION
Subtitle of host publicationNinth International Conference on Synchrotron Radiation Instrumentation
Pages1960-1963
Number of pages4
DOIs
Publication statusPublished - Mar 26 2007
EventSYNCHROTRON RADIATION INSTRUMENTATION: 9th International Conference on Synchrotron Radiation Instrumentation - Daegu, Korea, Republic of
Duration: May 28 2006Jun 28 2006

Publication series

NameAIP Conference Proceedings
Volume879
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

OtherSYNCHROTRON RADIATION INSTRUMENTATION: 9th International Conference on Synchrotron Radiation Instrumentation
CountryKorea, Republic of
CityDaegu
Period5/28/066/28/06

Keywords

  • Articular cartilage
  • Object direction
  • Refraction contrast
  • X-ray dark-field imaging

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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  • Cite this

    Shimao, D., Sugiyama, H., Kunisada, T., Hyodo, K., Mori, K., & Ando, M. (2007). On detailed contrast of biomedical object in X-ray dark-field imaging. In SYNCHROTRON RADIATION INSTRUMENTATION: Ninth International Conference on Synchrotron Radiation Instrumentation (pp. 1960-1963). (AIP Conference Proceedings; Vol. 879). https://doi.org/10.1063/1.2436458