Abstract
The procerebrum (PC) of the terrestrial mollusk Limax is a highly developed second-order olfactory center consisting of two electrophysiologically distinct populations of neurons: nonbursting (NB) and bursting (B). NB neurons are by far the more numerous of the two cell types. They receive direct synaptic inputs from afferent fibers from the tentacle ganglion, the primary olfactory center, and also receive periodic inhibitory postsynaptic potentials (IPSPs) from B neurons. Odor-evoked activity in the NB neurons was examined using perforated patch recordings. Stimulation of the superior tentacle with odorants resulted in inhibitory responses in 45% of NB neurons, while 11% of NB neurons showed an excitatory response. The specific response was reproducible in each neuron to the same odorant, suggesting the possibility that activity of NB neurons may encode odor identity. Analysis of the cycle-averaged membrane potential of NB neurons revealed a correlation between the firing rate and the membrane potential at the plateau phase between IPSPs. Also, the firing rate of NB neurons was affected by the frequency of the IPSPs. These results indicate the existence of two distinct mechanisms for the regulation of NB neuron activity.
| Original language | English |
|---|---|
| Pages (from-to) | 369-378 |
| Number of pages | 10 |
| Journal | Journal of Neurobiology |
| Volume | 58 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Feb 15 2004 |
| Externally published | Yes |
Fingerprint
Keywords
- Coding
- Mollusk
- Neural oscillation
- Olfaction
- Perforated patch recording
ASJC Scopus subject areas
- Neuroscience(all)
- Cellular and Molecular Neuroscience
Cite this
Odor-Evoked Responses in the Olfactory Center Neurons in the Terrestrial Slug. / Murakami, Masayoshi; Watanabe, Satoshi; Inoue, Tsuyoshi; Kirino, Yutaka.
In: Journal of Neurobiology, Vol. 58, No. 3, 15.02.2004, p. 369-378.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Odor-Evoked Responses in the Olfactory Center Neurons in the Terrestrial Slug
AU - Murakami, Masayoshi
AU - Watanabe, Satoshi
AU - Inoue, Tsuyoshi
AU - Kirino, Yutaka
PY - 2004/2/15
Y1 - 2004/2/15
N2 - The procerebrum (PC) of the terrestrial mollusk Limax is a highly developed second-order olfactory center consisting of two electrophysiologically distinct populations of neurons: nonbursting (NB) and bursting (B). NB neurons are by far the more numerous of the two cell types. They receive direct synaptic inputs from afferent fibers from the tentacle ganglion, the primary olfactory center, and also receive periodic inhibitory postsynaptic potentials (IPSPs) from B neurons. Odor-evoked activity in the NB neurons was examined using perforated patch recordings. Stimulation of the superior tentacle with odorants resulted in inhibitory responses in 45% of NB neurons, while 11% of NB neurons showed an excitatory response. The specific response was reproducible in each neuron to the same odorant, suggesting the possibility that activity of NB neurons may encode odor identity. Analysis of the cycle-averaged membrane potential of NB neurons revealed a correlation between the firing rate and the membrane potential at the plateau phase between IPSPs. Also, the firing rate of NB neurons was affected by the frequency of the IPSPs. These results indicate the existence of two distinct mechanisms for the regulation of NB neuron activity.
AB - The procerebrum (PC) of the terrestrial mollusk Limax is a highly developed second-order olfactory center consisting of two electrophysiologically distinct populations of neurons: nonbursting (NB) and bursting (B). NB neurons are by far the more numerous of the two cell types. They receive direct synaptic inputs from afferent fibers from the tentacle ganglion, the primary olfactory center, and also receive periodic inhibitory postsynaptic potentials (IPSPs) from B neurons. Odor-evoked activity in the NB neurons was examined using perforated patch recordings. Stimulation of the superior tentacle with odorants resulted in inhibitory responses in 45% of NB neurons, while 11% of NB neurons showed an excitatory response. The specific response was reproducible in each neuron to the same odorant, suggesting the possibility that activity of NB neurons may encode odor identity. Analysis of the cycle-averaged membrane potential of NB neurons revealed a correlation between the firing rate and the membrane potential at the plateau phase between IPSPs. Also, the firing rate of NB neurons was affected by the frequency of the IPSPs. These results indicate the existence of two distinct mechanisms for the regulation of NB neuron activity.
KW - Coding
KW - Mollusk
KW - Neural oscillation
KW - Olfaction
KW - Perforated patch recording
UR - http://www.scopus.com/inward/record.url?scp=1042301368&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1042301368&partnerID=8YFLogxK
U2 - 10.1002/neu.10295
DO - 10.1002/neu.10295
M3 - Article
C2 - 14750149
AN - SCOPUS:1042301368
VL - 58
SP - 369
EP - 378
JO - Developmental Neurobiology
JF - Developmental Neurobiology
SN - 1932-8451
IS - 3
ER -