Odor-Evoked Responses in the Olfactory Center Neurons in the Terrestrial Slug

Masayoshi Murakami, Satoshi Watanabe, Tsuyoshi Inoue, Yutaka Kirino

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The procerebrum (PC) of the terrestrial mollusk Limax is a highly developed second-order olfactory center consisting of two electrophysiologically distinct populations of neurons: nonbursting (NB) and bursting (B). NB neurons are by far the more numerous of the two cell types. They receive direct synaptic inputs from afferent fibers from the tentacle ganglion, the primary olfactory center, and also receive periodic inhibitory postsynaptic potentials (IPSPs) from B neurons. Odor-evoked activity in the NB neurons was examined using perforated patch recordings. Stimulation of the superior tentacle with odorants resulted in inhibitory responses in 45% of NB neurons, while 11% of NB neurons showed an excitatory response. The specific response was reproducible in each neuron to the same odorant, suggesting the possibility that activity of NB neurons may encode odor identity. Analysis of the cycle-averaged membrane potential of NB neurons revealed a correlation between the firing rate and the membrane potential at the plateau phase between IPSPs. Also, the firing rate of NB neurons was affected by the frequency of the IPSPs. These results indicate the existence of two distinct mechanisms for the regulation of NB neuron activity.

Original languageEnglish
Pages (from-to)369-378
Number of pages10
JournalJournal of Neurobiology
Volume58
Issue number3
DOIs
Publication statusPublished - Feb 15 2004
Externally publishedYes

Fingerprint

Gastropoda
Neurons
Inhibitory Postsynaptic Potentials
Membrane Potentials
Odorants
Mollusca
Ganglia

Keywords

  • Coding
  • Mollusk
  • Neural oscillation
  • Olfaction
  • Perforated patch recording

ASJC Scopus subject areas

  • Neuroscience(all)
  • Cellular and Molecular Neuroscience

Cite this

Odor-Evoked Responses in the Olfactory Center Neurons in the Terrestrial Slug. / Murakami, Masayoshi; Watanabe, Satoshi; Inoue, Tsuyoshi; Kirino, Yutaka.

In: Journal of Neurobiology, Vol. 58, No. 3, 15.02.2004, p. 369-378.

Research output: Contribution to journalArticle

Murakami, Masayoshi ; Watanabe, Satoshi ; Inoue, Tsuyoshi ; Kirino, Yutaka. / Odor-Evoked Responses in the Olfactory Center Neurons in the Terrestrial Slug. In: Journal of Neurobiology. 2004 ; Vol. 58, No. 3. pp. 369-378.
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