TY - JOUR
T1 - Ocular adnexal marginal zone lymphoma arising in a patient with IgG4-related ophthalmic disease
AU - Nishida, Kenji
AU - Sogabe, Yuka
AU - Makihara, Ayako
AU - Senoo, Akemi
AU - Morimoto, Hisanori
AU - Takeuchi, Mai
AU - Gion, Yuka
AU - Yoshino, Tadashi
AU - Sato, Yasuharu
N1 - Publisher Copyright:
© 2016, © 2016 Japan College of Rheumatology.
PY - 2019/3/4
Y1 - 2019/3/4
N2 - A 41-year-old man was diagnosed with immunoglobulin G4-related disease (IgG4-RD) in both eyelids 4 years ago and exhibited good response to steroid therapy. However, rapid swelling of the right eyelid lesion was recently observed. As IgG4-RD progression was suspected, biopsy was performed. Although the histology was consistent with IgG4-RD, the infiltrating large atypical lymphoid cells showed immunoglobulin light-chain restriction and IgH gene rearrangement. Consequently, he was diagnosed with extranodal marginal zone lymphoma with abundant IgG4-positive cells.
AB - A 41-year-old man was diagnosed with immunoglobulin G4-related disease (IgG4-RD) in both eyelids 4 years ago and exhibited good response to steroid therapy. However, rapid swelling of the right eyelid lesion was recently observed. As IgG4-RD progression was suspected, biopsy was performed. Although the histology was consistent with IgG4-RD, the infiltrating large atypical lymphoid cells showed immunoglobulin light-chain restriction and IgH gene rearrangement. Consequently, he was diagnosed with extranodal marginal zone lymphoma with abundant IgG4-positive cells.
KW - IgG4-related disease
KW - marginal zone lymphoma
KW - ocular adnexa
UR - http://www.scopus.com/inward/record.url?scp=84981206980&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84981206980&partnerID=8YFLogxK
U2 - 10.1080/14397595.2016.1216733
DO - 10.1080/14397595.2016.1216733
M3 - Article
C2 - 27686866
AN - SCOPUS:84981206980
VL - 29
SP - 383
EP - 387
JO - Japanese Journal of Rheumatology
JF - Japanese Journal of Rheumatology
SN - 1439-7595
IS - 2
ER -