Abstract
A 41-year-old man was diagnosed with immunoglobulin G4-related disease (IgG4-RD) in both eyelids 4 years ago and exhibited good response to steroid therapy. However, rapid swelling of the right eyelid lesion was recently observed. As IgG4-RD progression was suspected, biopsy was performed. Although the histology was consistent with IgG4-RD, the infiltrating large atypical lymphoid cells showed immunoglobulin light-chain restriction and IgH gene rearrangement. Consequently, he was diagnosed with extranodal marginal zone lymphoma with abundant IgG4-positive cells.
| Original language | English |
|---|---|
| Pages (from-to) | 1-5 |
| Number of pages | 5 |
| Journal | Modern Rheumatology |
| DOIs | |
| Publication status | Accepted/In press - Aug 10 2016 |
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Keywords
- IgG4-related disease
- marginal zone lymphoma
- ocular adnexa
ASJC Scopus subject areas
- Rheumatology
Cite this
Ocular adnexal marginal zone lymphoma arising in a patient with IgG4-related ophthalmic disease. / Nishida, Kenji; Sogabe, Yuka; Makihara, Ayako; Senoo, Akemi; Morimoto, Hisanori; Takeuchi, Mai; Gion, Yuka; Yoshino, Tadashi; Sato, Yasuharu.
In: Modern Rheumatology, 10.08.2016, p. 1-5.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ocular adnexal marginal zone lymphoma arising in a patient with IgG4-related ophthalmic disease
AU - Nishida, Kenji
AU - Sogabe, Yuka
AU - Makihara, Ayako
AU - Senoo, Akemi
AU - Morimoto, Hisanori
AU - Takeuchi, Mai
AU - Gion, Yuka
AU - Yoshino, Tadashi
AU - Sato, Yasuharu
PY - 2016/8/10
Y1 - 2016/8/10
N2 - A 41-year-old man was diagnosed with immunoglobulin G4-related disease (IgG4-RD) in both eyelids 4 years ago and exhibited good response to steroid therapy. However, rapid swelling of the right eyelid lesion was recently observed. As IgG4-RD progression was suspected, biopsy was performed. Although the histology was consistent with IgG4-RD, the infiltrating large atypical lymphoid cells showed immunoglobulin light-chain restriction and IgH gene rearrangement. Consequently, he was diagnosed with extranodal marginal zone lymphoma with abundant IgG4-positive cells.
AB - A 41-year-old man was diagnosed with immunoglobulin G4-related disease (IgG4-RD) in both eyelids 4 years ago and exhibited good response to steroid therapy. However, rapid swelling of the right eyelid lesion was recently observed. As IgG4-RD progression was suspected, biopsy was performed. Although the histology was consistent with IgG4-RD, the infiltrating large atypical lymphoid cells showed immunoglobulin light-chain restriction and IgH gene rearrangement. Consequently, he was diagnosed with extranodal marginal zone lymphoma with abundant IgG4-positive cells.
KW - IgG4-related disease
KW - marginal zone lymphoma
KW - ocular adnexa
UR - http://www.scopus.com/inward/record.url?scp=84981206980&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84981206980&partnerID=8YFLogxK
U2 - 10.1080/14397595.2016.1216733
DO - 10.1080/14397595.2016.1216733
M3 - Article
C2 - 27686866
AN - SCOPUS:84981206980
SP - 1
EP - 5
JO - Modern Rheumatology
JF - Modern Rheumatology
SN - 1439-7595
ER -