Abstract
A 59-year-old man was admitted in July, 1985 because of generalized lymphadenopathy and hypercalcemia. The biopsy specimen of the left inguinal lymph node showed diffuse large cell lymphoma. He achieved a complete remission (CR) in July, 1986 by CHOP therapy. In January, 1992, he visited the outpatient clinic with splenomegaly, and swelling of the left axillary and left supraclavicular lymph nodes. The biopsy specimen of the axillary lymph node showed follicular small cleaved cell lymphoma. Because the spleen and the lymph nodes regressed after the biopsy, he has been followed up without any specific treatment for lymphoma. Histologic change from low-grade lymphoma into more aggressive histologic pattern is well documented. However the converse phenomenon, occurrence of low-grade lymphoma after intermediate-, or high-grade lymphoma has rarely been reported. Histological examination is mandatory when a patient with diffuse large cell lymphoma is suspected to have relapsing disease after the long-term CR.
| Original language | English |
|---|---|
| Pages (from-to) | 676-681 |
| Number of pages | 6 |
| Journal | [Rinshō ketsueki] The Japanese journal of clinical hematology |
| Volume | 35 |
| Issue number | 7 |
| Publication status | Published - Jul 1994 |
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Occurrence of follicular small cleaved cell lymphoma following chemotherapy for diffuse large cell lymphoma. / Saito, Shinya; Hayashi, K.; Ohnoshi, T.; Kawashima, K.; Matsutomo, S.; Tagawa, S.; Yoshino, Tadashi; Nishiuchi, R.; Kimura, I.
In: [Rinshō ketsueki] The Japanese journal of clinical hematology, Vol. 35, No. 7, 07.1994, p. 676-681.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Occurrence of follicular small cleaved cell lymphoma following chemotherapy for diffuse large cell lymphoma
AU - Saito, Shinya
AU - Hayashi, K.
AU - Ohnoshi, T.
AU - Kawashima, K.
AU - Matsutomo, S.
AU - Tagawa, S.
AU - Yoshino, Tadashi
AU - Nishiuchi, R.
AU - Kimura, I.
PY - 1994/7
Y1 - 1994/7
N2 - A 59-year-old man was admitted in July, 1985 because of generalized lymphadenopathy and hypercalcemia. The biopsy specimen of the left inguinal lymph node showed diffuse large cell lymphoma. He achieved a complete remission (CR) in July, 1986 by CHOP therapy. In January, 1992, he visited the outpatient clinic with splenomegaly, and swelling of the left axillary and left supraclavicular lymph nodes. The biopsy specimen of the axillary lymph node showed follicular small cleaved cell lymphoma. Because the spleen and the lymph nodes regressed after the biopsy, he has been followed up without any specific treatment for lymphoma. Histologic change from low-grade lymphoma into more aggressive histologic pattern is well documented. However the converse phenomenon, occurrence of low-grade lymphoma after intermediate-, or high-grade lymphoma has rarely been reported. Histological examination is mandatory when a patient with diffuse large cell lymphoma is suspected to have relapsing disease after the long-term CR.
AB - A 59-year-old man was admitted in July, 1985 because of generalized lymphadenopathy and hypercalcemia. The biopsy specimen of the left inguinal lymph node showed diffuse large cell lymphoma. He achieved a complete remission (CR) in July, 1986 by CHOP therapy. In January, 1992, he visited the outpatient clinic with splenomegaly, and swelling of the left axillary and left supraclavicular lymph nodes. The biopsy specimen of the axillary lymph node showed follicular small cleaved cell lymphoma. Because the spleen and the lymph nodes regressed after the biopsy, he has been followed up without any specific treatment for lymphoma. Histologic change from low-grade lymphoma into more aggressive histologic pattern is well documented. However the converse phenomenon, occurrence of low-grade lymphoma after intermediate-, or high-grade lymphoma has rarely been reported. Histological examination is mandatory when a patient with diffuse large cell lymphoma is suspected to have relapsing disease after the long-term CR.
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UR - http://www.scopus.com/inward/citedby.url?scp=0028471584&partnerID=8YFLogxK
M3 - Article
VL - 35
SP - 676
EP - 681
JO - [Rinsho ketsueki] The Japanese journal of clinical hematology
JF - [Rinsho ketsueki] The Japanese journal of clinical hematology
SN - 0485-1439
IS - 7
ER -