Occurrence of bilaterally independent epileptic spasms after a corpus callosotomy in West syndrome

Katsuhiro Kobayashi, Fumika Endoh, Yoshihiro Toda, Makio Oka, Hiroshi Baba, Yoko Ohtsuka, Harumi Yoshinaga

Research output: Contribution to journalArticle

5 Citations (Scopus)


We report a patient with intractable West syndrome whose epileptic spasms (ESs) were initially bilaterally synchronous, as is typical; after a complete corpus callosotomy, however, bilaterally independent ESs originated in either hemisphere. Activity of probable cortical origin associated with ESs was detected by observing ictal gamma oscillations. Brain MRI revealed no structural abnormality before surgery. This case suggests that ESs with a hemispheric origin may appear generalized because of synchronizing effects in the corpus callosum in some patients.

Original languageEnglish
Pages (from-to)132-135
Number of pages4
JournalBrain and Development
Issue number1
Publication statusPublished - Jan 1 2016



  • Bilateral independence
  • Callosotomy
  • Epileptic spasms
  • West syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Clinical Neurology

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