TY - JOUR
T1 - Occurrence of bilaterally independent epileptic spasms after a corpus callosotomy in West syndrome
AU - Kobayashi, Katsuhiro
AU - Endoh, Fumika
AU - Toda, Yoshihiro
AU - Oka, Makio
AU - Baba, Hiroshi
AU - Ohtsuka, Yoko
AU - Yoshinaga, Harumi
PY - 2016/1/1
Y1 - 2016/1/1
N2 - We report a patient with intractable West syndrome whose epileptic spasms (ESs) were initially bilaterally synchronous, as is typical; after a complete corpus callosotomy, however, bilaterally independent ESs originated in either hemisphere. Activity of probable cortical origin associated with ESs was detected by observing ictal gamma oscillations. Brain MRI revealed no structural abnormality before surgery. This case suggests that ESs with a hemispheric origin may appear generalized because of synchronizing effects in the corpus callosum in some patients.
AB - We report a patient with intractable West syndrome whose epileptic spasms (ESs) were initially bilaterally synchronous, as is typical; after a complete corpus callosotomy, however, bilaterally independent ESs originated in either hemisphere. Activity of probable cortical origin associated with ESs was detected by observing ictal gamma oscillations. Brain MRI revealed no structural abnormality before surgery. This case suggests that ESs with a hemispheric origin may appear generalized because of synchronizing effects in the corpus callosum in some patients.
KW - Bilateral independence
KW - Callosotomy
KW - Epileptic spasms
KW - West syndrome
UR - http://www.scopus.com/inward/record.url?scp=84929438848&partnerID=8YFLogxK
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U2 - 10.1016/j.braindev.2015.05.003
DO - 10.1016/j.braindev.2015.05.003
M3 - Article
C2 - 25998967
AN - SCOPUS:84929438848
VL - 38
SP - 132
EP - 135
JO - Brain and Development
JF - Brain and Development
SN - 0387-7604
IS - 1
ER -