Abstract
We report a patient with intractable West syndrome whose epileptic spasms (ESs) were initially bilaterally synchronous, as is typical; after a complete corpus callosotomy, however, bilaterally independent ESs originated in either hemisphere. Activity of probable cortical origin associated with ESs was detected by observing ictal gamma oscillations. Brain MRI revealed no structural abnormality before surgery. This case suggests that ESs with a hemispheric origin may appear generalized because of synchronizing effects in the corpus callosum in some patients.
| Original language | English |
|---|---|
| Journal | Brain and Development |
| DOIs | |
| Publication status | Accepted/In press - 2015 |
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Keywords
- Bilateral independence
- Callosotomy
- Epileptic spasms
- West syndrome
ASJC Scopus subject areas
- Clinical Neurology
- Developmental Neuroscience
- Pediatrics, Perinatology, and Child Health
Cite this
Occurrence of bilaterally independent epileptic spasms after a corpus callosotomy in West syndrome. / Kobayashi, Katsuhiro; Endoh, Fumika; Toda, Yoshihiro; Oka, Makio; Baba, Hiroshi; Ohtsuka, Yoko; Yoshinaga, Harumi.
In: Brain and Development, 2015.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Occurrence of bilaterally independent epileptic spasms after a corpus callosotomy in West syndrome
AU - Kobayashi, Katsuhiro
AU - Endoh, Fumika
AU - Toda, Yoshihiro
AU - Oka, Makio
AU - Baba, Hiroshi
AU - Ohtsuka, Yoko
AU - Yoshinaga, Harumi
PY - 2015
Y1 - 2015
N2 - We report a patient with intractable West syndrome whose epileptic spasms (ESs) were initially bilaterally synchronous, as is typical; after a complete corpus callosotomy, however, bilaterally independent ESs originated in either hemisphere. Activity of probable cortical origin associated with ESs was detected by observing ictal gamma oscillations. Brain MRI revealed no structural abnormality before surgery. This case suggests that ESs with a hemispheric origin may appear generalized because of synchronizing effects in the corpus callosum in some patients.
AB - We report a patient with intractable West syndrome whose epileptic spasms (ESs) were initially bilaterally synchronous, as is typical; after a complete corpus callosotomy, however, bilaterally independent ESs originated in either hemisphere. Activity of probable cortical origin associated with ESs was detected by observing ictal gamma oscillations. Brain MRI revealed no structural abnormality before surgery. This case suggests that ESs with a hemispheric origin may appear generalized because of synchronizing effects in the corpus callosum in some patients.
KW - Bilateral independence
KW - Callosotomy
KW - Epileptic spasms
KW - West syndrome
UR - http://www.scopus.com/inward/record.url?scp=84929438848&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929438848&partnerID=8YFLogxK
U2 - 10.1016/j.braindev.2015.05.003
DO - 10.1016/j.braindev.2015.05.003
M3 - Article
C2 - 25998967
AN - SCOPUS:84929438848
JO - Brain and Development
JF - Brain and Development
SN - 0387-7604
ER -