Occurrence of bilaterally independent epileptic spasms after a corpus callosotomy in West syndrome

Katsuhiro Kobayashi; Fumika Endoh; Yoshihiro Toda; Makio Oka; Hiroshi Baba; Yoko Ohtsuka; Harumi Yoshinaga

doi:10.1016/j.braindev.2015.05.003

Occurrence of bilaterally independent epileptic spasms after a corpus callosotomy in West syndrome

Katsuhiro Kobayashi, Fumika Endoh, Yoshihiro Toda, Makio Oka, Hiroshi Baba, Yoko Ohtsuka, Harumi Yoshinaga

Research output: Contribution to journal › Article

5 Citations (Scopus)

Abstract

We report a patient with intractable West syndrome whose epileptic spasms (ESs) were initially bilaterally synchronous, as is typical; after a complete corpus callosotomy, however, bilaterally independent ESs originated in either hemisphere. Activity of probable cortical origin associated with ESs was detected by observing ictal gamma oscillations. Brain MRI revealed no structural abnormality before surgery. This case suggests that ESs with a hemispheric origin may appear generalized because of synchronizing effects in the corpus callosum in some patients.

Original language	English
Pages (from-to)	132-135
Number of pages	4
Journal	Brain and Development
Volume	38
Issue number	1
DOIs	https://doi.org/10.1016/j.braindev.2015.05.003
Publication status	Published - Jan 1 2016

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Keywords

Bilateral independence
Callosotomy
Epileptic spasms
West syndrome

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Developmental Neuroscience
Clinical Neurology

Cite this

Kobayashi, K., Endoh, F., Toda, Y., Oka, M., Baba, H., Ohtsuka, Y., & Yoshinaga, H. (2016). Occurrence of bilaterally independent epileptic spasms after a corpus callosotomy in West syndrome. Brain and Development, 38(1), 132-135. https://doi.org/10.1016/j.braindev.2015.05.003

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10.1016/j.braindev.2015.05.003