Nucleotide sequence of nuclear 5.4 S RNA of mouse cells

Nobuyuki Kato, Fumio Harada

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

The nucleotide sequence of nuclear 5.4 S RNA, a new species of small nuclear RNA (snRNA) of mouse cells, was determined. The 5.4 S RNA consists of 138 nucleotide residues containing 1 mol each of 2,2,7-trimethylguanosine (m2,2,73 G), 2′-O-methyladenosine (Am), 2′-O-methyluridine (Um) and pseudouridine as modified nucleosides. This RNA has a cap structure, m2,2,73 GpppAm-, at its 5′-terminus and sequences complementary to the terminal consensus sequences of introns. The sequence complementary to the 5′-splice junction, A-U-C-C-ψ-U-A-C-C-U-G, is very similar to the 5′-terminal sequence of U1 RNA.

Original languageEnglish
Pages (from-to)127-131
Number of pages5
JournalBBA - Gene Structure and Expression
Volume782
Issue number2
DOIs
Publication statusPublished - Jun 16 1984
Externally publishedYes

Keywords

  • (Mouse)
  • 5.4 S RNA
  • Nucleotide sequence
  • Secondary structure
  • Splicing
  • small nuclear RNA

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics

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