Nucleation and growth of apatite on an anatase layer irradiated with UV light under different environmental conditions

Keita Uetsuki, Shinsuke Nakai, Yuki Shirosaki, Satoshi Hayakawa, Akiyoshi Osaka

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Implant surfaces must sometimes be modified to form strong bonds to host tissues. The method of depositing an anatase layer on chemically pure titanium by chemical oxidation with H2O2 and subsequent calcination (CHT) is known to deposit apatite under physiological conditions; it thus exhibits bone-bonding ability. UV irradiation should affect the bonding ability because the CHT anatase layer would experience certain chemical modifications, such as a decrease or an increase in the number of Ti-OH and Ti-O(H)-Ti sites; these sites are considered active sites for apatite nucleation. When in vitro apatite deposition was examined, using Kokubo's simulated body fluid, UV irradiation in air reduced the apatite-forming ability of the CHT anatase layer, and UV irradiation on the samples in water enhanced the ability. These results were correlated to changes in the Ti-OH and Ti-O(H)-Ti sites, as determined by O 1s X-ray photoelectron spectroscopy. Analysis of the number and size of the semi-spherical apatite particles and their surface coverage led to a model: proper assembly of the Ti-OH and Ti-O(H)-Ti sites should only give rise to the induction of apatite nucleation, analogous to topotaxy effects.

Original languageEnglish
Pages (from-to)712-719
Number of pages8
JournalJournal of Biomedical Materials Research - Part A
Volume101 A
Issue number3
DOIs
Publication statusPublished - Mar 2013

Fingerprint

Apatites
Apatite
Ultraviolet radiation
Titanium dioxide
Nucleation
Irradiation
Body fluids
Chemical modification
Titanium
Calcination
titanium dioxide
Bone
Deposits
X ray photoelectron spectroscopy
Tissue
Oxidation
Water
Air

Keywords

  • Anatase
  • Apatite
  • Nucleation and growth
  • Surface chemical state
  • UV irradiation

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Ceramics and Composites
  • Metals and Alloys

Cite this

Nucleation and growth of apatite on an anatase layer irradiated with UV light under different environmental conditions. / Uetsuki, Keita; Nakai, Shinsuke; Shirosaki, Yuki; Hayakawa, Satoshi; Osaka, Akiyoshi.

In: Journal of Biomedical Materials Research - Part A, Vol. 101 A, No. 3, 03.2013, p. 712-719.

Research output: Contribution to journalArticle

@article{d40b229b25eb4f6aa47b9159b9aa5d02,
title = "Nucleation and growth of apatite on an anatase layer irradiated with UV light under different environmental conditions",
abstract = "Implant surfaces must sometimes be modified to form strong bonds to host tissues. The method of depositing an anatase layer on chemically pure titanium by chemical oxidation with H2O2 and subsequent calcination (CHT) is known to deposit apatite under physiological conditions; it thus exhibits bone-bonding ability. UV irradiation should affect the bonding ability because the CHT anatase layer would experience certain chemical modifications, such as a decrease or an increase in the number of Ti-OH and Ti-O(H)-Ti sites; these sites are considered active sites for apatite nucleation. When in vitro apatite deposition was examined, using Kokubo's simulated body fluid, UV irradiation in air reduced the apatite-forming ability of the CHT anatase layer, and UV irradiation on the samples in water enhanced the ability. These results were correlated to changes in the Ti-OH and Ti-O(H)-Ti sites, as determined by O 1s X-ray photoelectron spectroscopy. Analysis of the number and size of the semi-spherical apatite particles and their surface coverage led to a model: proper assembly of the Ti-OH and Ti-O(H)-Ti sites should only give rise to the induction of apatite nucleation, analogous to topotaxy effects.",
keywords = "Anatase, Apatite, Nucleation and growth, Surface chemical state, UV irradiation",
author = "Keita Uetsuki and Shinsuke Nakai and Yuki Shirosaki and Satoshi Hayakawa and Akiyoshi Osaka",
year = "2013",
month = "3",
doi = "10.1002/jbm.a.34370",
language = "English",
volume = "101 A",
pages = "712--719",
journal = "Journal of Biomedical Materials Research - Part A",
issn = "1549-3296",
publisher = "John Wiley and Sons Inc.",
number = "3",

}

TY - JOUR

T1 - Nucleation and growth of apatite on an anatase layer irradiated with UV light under different environmental conditions

AU - Uetsuki, Keita

AU - Nakai, Shinsuke

AU - Shirosaki, Yuki

AU - Hayakawa, Satoshi

AU - Osaka, Akiyoshi

PY - 2013/3

Y1 - 2013/3

N2 - Implant surfaces must sometimes be modified to form strong bonds to host tissues. The method of depositing an anatase layer on chemically pure titanium by chemical oxidation with H2O2 and subsequent calcination (CHT) is known to deposit apatite under physiological conditions; it thus exhibits bone-bonding ability. UV irradiation should affect the bonding ability because the CHT anatase layer would experience certain chemical modifications, such as a decrease or an increase in the number of Ti-OH and Ti-O(H)-Ti sites; these sites are considered active sites for apatite nucleation. When in vitro apatite deposition was examined, using Kokubo's simulated body fluid, UV irradiation in air reduced the apatite-forming ability of the CHT anatase layer, and UV irradiation on the samples in water enhanced the ability. These results were correlated to changes in the Ti-OH and Ti-O(H)-Ti sites, as determined by O 1s X-ray photoelectron spectroscopy. Analysis of the number and size of the semi-spherical apatite particles and their surface coverage led to a model: proper assembly of the Ti-OH and Ti-O(H)-Ti sites should only give rise to the induction of apatite nucleation, analogous to topotaxy effects.

AB - Implant surfaces must sometimes be modified to form strong bonds to host tissues. The method of depositing an anatase layer on chemically pure titanium by chemical oxidation with H2O2 and subsequent calcination (CHT) is known to deposit apatite under physiological conditions; it thus exhibits bone-bonding ability. UV irradiation should affect the bonding ability because the CHT anatase layer would experience certain chemical modifications, such as a decrease or an increase in the number of Ti-OH and Ti-O(H)-Ti sites; these sites are considered active sites for apatite nucleation. When in vitro apatite deposition was examined, using Kokubo's simulated body fluid, UV irradiation in air reduced the apatite-forming ability of the CHT anatase layer, and UV irradiation on the samples in water enhanced the ability. These results were correlated to changes in the Ti-OH and Ti-O(H)-Ti sites, as determined by O 1s X-ray photoelectron spectroscopy. Analysis of the number and size of the semi-spherical apatite particles and their surface coverage led to a model: proper assembly of the Ti-OH and Ti-O(H)-Ti sites should only give rise to the induction of apatite nucleation, analogous to topotaxy effects.

KW - Anatase

KW - Apatite

KW - Nucleation and growth

KW - Surface chemical state

KW - UV irradiation

UR - http://www.scopus.com/inward/record.url?scp=84876181546&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84876181546&partnerID=8YFLogxK

U2 - 10.1002/jbm.a.34370

DO - 10.1002/jbm.a.34370

M3 - Article

C2 - 22941932

AN - SCOPUS:84876181546

VL - 101 A

SP - 712

EP - 719

JO - Journal of Biomedical Materials Research - Part A

JF - Journal of Biomedical Materials Research - Part A

SN - 1549-3296

IS - 3

ER -