Abstract
A novel 6/8/6-membered taxane with a rare C-12(13)-double bond and rare 2(3→20)abeotaxane were isolated from the needles of Taxus canadensis. Their structures were characterized as 7β,9α,10β-triacetoxytaxa- 4(20),12-diene-2α,5α,11β-triol (1) and 2α,7β, 10β- triacetoxy-5α-hydroxy-2(3→20)abeotaxa-4(20),11-diene- 9,13-dione (2) on the basis of 1D and 2D spectroscopic data. 1 is the first example of a natural taxane without substitution at both C-13 and C-14.
| Original language | English |
|---|---|
| Pages (from-to) | 1698-1701 |
| Number of pages | 4 |
| Journal | Bioscience, Biotechnology and Biochemistry |
| Volume | 75 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 2011 |
| Externally published | Yes |
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Keywords
- 12-diene
- Isolation
- Needle
- Taxa-4(20)
- Taxane
- Taxus canadensis
ASJC Scopus subject areas
- Biotechnology
- Biochemistry
- Molecular Biology
- Applied Microbiology and Biotechnology
- Analytical Chemistry
- Organic Chemistry
Cite this
Novel taxa-4(20),12-diene and 2(3→20)abeotaxane from needles of Taxus canadensis. / Ni, Zhi Yu; Wu, Yi Bing; Zhang, Man Li; Wang, Yu Fang; Dong, Mei; Sauriol, Françoise; Huo, Chang Hong; Shi, Qing Wen; Gu, Yu Cheng; Kiyota, Hiromasa; Cong, Bin.
In: Bioscience, Biotechnology and Biochemistry, Vol. 75, No. 9, 2011, p. 1698-1701.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Novel taxa-4(20),12-diene and 2(3→20)abeotaxane from needles of Taxus canadensis
AU - Ni, Zhi Yu
AU - Wu, Yi Bing
AU - Zhang, Man Li
AU - Wang, Yu Fang
AU - Dong, Mei
AU - Sauriol, Françoise
AU - Huo, Chang Hong
AU - Shi, Qing Wen
AU - Gu, Yu Cheng
AU - Kiyota, Hiromasa
AU - Cong, Bin
PY - 2011
Y1 - 2011
N2 - A novel 6/8/6-membered taxane with a rare C-12(13)-double bond and rare 2(3→20)abeotaxane were isolated from the needles of Taxus canadensis. Their structures were characterized as 7β,9α,10β-triacetoxytaxa- 4(20),12-diene-2α,5α,11β-triol (1) and 2α,7β, 10β- triacetoxy-5α-hydroxy-2(3→20)abeotaxa-4(20),11-diene- 9,13-dione (2) on the basis of 1D and 2D spectroscopic data. 1 is the first example of a natural taxane without substitution at both C-13 and C-14.
AB - A novel 6/8/6-membered taxane with a rare C-12(13)-double bond and rare 2(3→20)abeotaxane were isolated from the needles of Taxus canadensis. Their structures were characterized as 7β,9α,10β-triacetoxytaxa- 4(20),12-diene-2α,5α,11β-triol (1) and 2α,7β, 10β- triacetoxy-5α-hydroxy-2(3→20)abeotaxa-4(20),11-diene- 9,13-dione (2) on the basis of 1D and 2D spectroscopic data. 1 is the first example of a natural taxane without substitution at both C-13 and C-14.
KW - 12-diene
KW - Isolation
KW - Needle
KW - Taxa-4(20)
KW - Taxane
KW - Taxus canadensis
UR - http://www.scopus.com/inward/record.url?scp=80053134676&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80053134676&partnerID=8YFLogxK
U2 - 10.1271/bbb.110223
DO - 10.1271/bbb.110223
M3 - Article
C2 - 21897043
AN - SCOPUS:80053134676
VL - 75
SP - 1698
EP - 1701
JO - Bioscience, Biotechnology and Biochemistry
JF - Bioscience, Biotechnology and Biochemistry
SN - 0916-8451
IS - 9
ER -