Novel synthesis of benzoxazoles from o-nitrophenols and amines

Hiromi Nishioka, Yukiko Ohmori, Yumiko Iba, Eri Tsuda, Takashi Harayama

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

o-Nitrophenols and o-nitroaniline were reacted with amines at 210-215°C to produce the corresponding benzoxazoles and benzimidazoles, respectively, in moderate yields. The reactions between o-nitrophenols containing a CO2Me or OMe group on their benzene rings and N,N-diethylaniline were examined to investigate the effects of the position and electronic character of these substituents on the formation of the oxazole ring.

Original languageEnglish
Pages (from-to)193-198
Number of pages6
JournalHeterocycles
Volume64
DOIs
Publication statusPublished - Dec 31 2004

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Benzoxazoles
Nitrophenols
Amines
Oxazoles
Benzimidazoles
Benzene

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Novel synthesis of benzoxazoles from o-nitrophenols and amines. / Nishioka, Hiromi; Ohmori, Yukiko; Iba, Yumiko; Tsuda, Eri; Harayama, Takashi.

In: Heterocycles, Vol. 64, 31.12.2004, p. 193-198.

Research output: Contribution to journalArticle

Nishioka, Hiromi ; Ohmori, Yukiko ; Iba, Yumiko ; Tsuda, Eri ; Harayama, Takashi. / Novel synthesis of benzoxazoles from o-nitrophenols and amines. In: Heterocycles. 2004 ; Vol. 64. pp. 193-198.
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