Abstract
The thermal cyclization of γ-aminoallylstannane (8) having an aldehyde group gave β-hydroxypyrrolidine derivative (9a) as a sole product. This methodology was applied successfully to the total synthesis of (+)-preussin.
| Original language | English |
|---|---|
| Pages (from-to) | 335-348 |
| Number of pages | 14 |
| Journal | Heterocycles |
| Volume | 46 |
| Issue number | 1 |
| Publication status | Published - Dec 1 1997 |
| Externally published | Yes |
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmacology
- Organic Chemistry
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Kadota, I., Saya, S., & Yamamoto, Y. (1997). Novel route to the synthesis of hydroxylated pyrrolidine derivatives via the intramolecular reaction of γ-aminoallylstannane with aldehyde. Total synthesis of (+)-preussin. Heterocycles, 46(1), 335-348.