Novel percutaneous catheter thrombectomy in acute masssive pulmonary embolism

Rotational bidirectional thrombectomy (ROBOT)

Masashi Yoshida, Ichiro Inoue, Takuji Kawagoe, Masaharu Ishihara, Yuji Shimatani, Satoshi Kurisu, Kengo Fukushima Kusano, Tohru Ohe

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background: Although thrombolysis is a standard therapy in cases of pulmonary embolism (PE), fatal outcome is often observed. We designed and investigated the efficacy of a novel percutaneous catheter therapy, rotational bidirectional thrombectomy (ROBOT), for PE. Methods and Results: Eighteen patients with acute massive PE (Miller score > 20) were included in this study. We separated them into two groups [group A (n = 10), thrombolysis; group B (n = 8): thrombolysis and ROBOT or ROBOT alone]. There was no difference in the hemodynamic indices between the groups at diagnosis. ROBOT was designed to fragment emboli by rotating a regular pigtail catheter. Three deaths occurred in group A because of hemodynamic impairment, but there was no death in group B. One day after treatment, systolic pulmonary artery pressure had decreased from 53 ± 8 to 30 ± 8 mm Hg (P <0.05) in group B and from 54 ± 5 to 42 ± 19 mm Hg (NS) in group A. The hospitalization period in group B was shorter than that in group A (17 ± 6 vs. 27 ± 10 days, P <0.05). Conclusion: ROBOT therapy results in a significant, rapid improvement in the hemodynamic situation and in a better outcome than conventional therapy in patients with acute massive pulmonary embolism.

Original languageEnglish
Pages (from-to)112-117
Number of pages6
JournalCatheterization and Cardiovascular Interventions
Volume68
Issue number1
DOIs
Publication statusPublished - Jul 2006

Fingerprint

Thrombectomy
Pulmonary Embolism
Catheters
Hemodynamics
Therapeutics
Fatal Outcome
Embolism
Pulmonary Artery
Hospitalization
Pressure

Keywords

  • Pulmonary embolism
  • Thrombectomy
  • Thrombolysis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Novel percutaneous catheter thrombectomy in acute masssive pulmonary embolism : Rotational bidirectional thrombectomy (ROBOT). / Yoshida, Masashi; Inoue, Ichiro; Kawagoe, Takuji; Ishihara, Masaharu; Shimatani, Yuji; Kurisu, Satoshi; Kusano, Kengo Fukushima; Ohe, Tohru.

In: Catheterization and Cardiovascular Interventions, Vol. 68, No. 1, 07.2006, p. 112-117.

Research output: Contribution to journalArticle

Yoshida, Masashi ; Inoue, Ichiro ; Kawagoe, Takuji ; Ishihara, Masaharu ; Shimatani, Yuji ; Kurisu, Satoshi ; Kusano, Kengo Fukushima ; Ohe, Tohru. / Novel percutaneous catheter thrombectomy in acute masssive pulmonary embolism : Rotational bidirectional thrombectomy (ROBOT). In: Catheterization and Cardiovascular Interventions. 2006 ; Vol. 68, No. 1. pp. 112-117.
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