Novel neuroimaging technique and measurement of contrast sensitivity with wide-view stimuli in human visual cortex

Tianyi Yan, Bin Wang, Jinglong Wu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Using a novel wide-view visual presentation system for vision research developed by us and visual retinotopic mapping functional magnetic resonance imaging (fMRI). We have investigated the variation of BLOD response, in three visual areas (V1-V3), as a function of visual retintotopic areas and five contrast levels (96%, 48%, 24%, 12% and 6%). Each visual area was identified in each subject using a combination of retinotopic mapping methods and cortical flattening techniques. A checkerboard patterns with five level contrasts were used as the stimuli in this study. We also constructed BLOD responses amplitude tuning curves, averaged across subjects, for three visual areas (V1-V3) and three eccentricities (0-20°, 20-40°, 40-60°). The result indicated that the peripheral stimulation would lead to lower BLOD responses, compared with the visual areas relative to central field stimulation. The present signal change of each visual area is consistent with the known physiological properties of cells in the corresponding macaque visual areas in previous functional imaging studies. In presented study, we confirmed visual areas V3 showed more sensitivity to contrast, than V2, and than V1 in central and peri-central visual area. More importantly, we revealed the biological responses for peripheral visual areas (40-60°), which the V1-V3 had BLOD signal change only for higher contrast (96%and 48%), but no BLOD response for lower contrast (24%, 12% and 6%).

Original languageEnglish
Title of host publicationProceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010
Pages443-447
Number of pages5
Volume1
DOIs
Publication statusPublished - 2010
Event3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010 - Yantai, China
Duration: Oct 16 2010Oct 18 2010

Other

Other3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010
CountryChina
CityYantai
Period10/16/1010/18/10

Fingerprint

Neuroimaging
Contrast Sensitivity
Macaca
Visual Cortex
Magnetic Resonance Imaging
Research
Tuning
Imaging techniques

Keywords

  • Contrast
  • fMRI
  • Retinotopy
  • Visual areas

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

Cite this

Yan, T., Wang, B., & Wu, J. (2010). Novel neuroimaging technique and measurement of contrast sensitivity with wide-view stimuli in human visual cortex. In Proceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010 (Vol. 1, pp. 443-447). [5639780] https://doi.org/10.1109/BMEI.2010.5639780

Novel neuroimaging technique and measurement of contrast sensitivity with wide-view stimuli in human visual cortex. / Yan, Tianyi; Wang, Bin; Wu, Jinglong.

Proceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010. Vol. 1 2010. p. 443-447 5639780.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Yan, T, Wang, B & Wu, J 2010, Novel neuroimaging technique and measurement of contrast sensitivity with wide-view stimuli in human visual cortex. in Proceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010. vol. 1, 5639780, pp. 443-447, 3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010, Yantai, China, 10/16/10. https://doi.org/10.1109/BMEI.2010.5639780
Yan T, Wang B, Wu J. Novel neuroimaging technique and measurement of contrast sensitivity with wide-view stimuli in human visual cortex. In Proceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010. Vol. 1. 2010. p. 443-447. 5639780 https://doi.org/10.1109/BMEI.2010.5639780
Yan, Tianyi ; Wang, Bin ; Wu, Jinglong. / Novel neuroimaging technique and measurement of contrast sensitivity with wide-view stimuli in human visual cortex. Proceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010. Vol. 1 2010. pp. 443-447
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