Novel 3D-CT evaluation of carotid stent volume: Greater chronological expansion of stents in patients with vulnerable plaques

Hisakazu Itami, Koji Tokunaga, Yu Okuma, Tomohito Hishikawa, Kenji Sugiu, Kentaro Ida, Isao Date

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction: Although self-expanding carotid stents may dilate gradually, the degrees of residual stenosis have been quantified by the NASCET criteria, which is too simple to reflect the configuration of the stented artery. We measured the volumes of the stent lumens chronologically by 3D-CT in patients after carotid artery stenting (CAS), and analyzed the correlations between the volume change and medical factors. Methods: Fourteen patients with carotid artery stenosis were treated using self-expanding, open-cell stents. All patients underwent preoperative plaque MRI (magnetization-prepared rapid acquisition gradient-echo, MPRAGE) and chronological 3D-CT examinations of their stents immediately after their placement and 1 day, 1 week, and 1 month after the procedure. The volume of the stent lumen was measured using a 3D workstation. The correlations between stent volume and various factors including the presence of underlying diseases, plaque characteristics, and the results of the CAS procedure were analyzed. Results: Stent volume gradually increased in each case and had increased by 1.04-1.55 (mean, 1.25)-fold at 1 postoperative month. The presence of underlying medical diseases, plaque length, the degree of residual stenosis immediately after CAS, and plaque calcification did not have an impact on the change in stent volume. On the other hand, the stent volume increase was significantly larger in the patients with vulnerable plaques that demonstrated high MPRAGE signal intensity (P <0.05). Conclusions: A 3D-CT examination is useful for precisely measuring stent volume. Self-expanding stents in carotid arteries containing vulnerable plaques expand significantly more than those without such plaques in a follow-up period.

Original languageEnglish
Pages (from-to)1153-1160
Number of pages8
JournalNeuroradiology
Volume55
Issue number9
DOIs
Publication statusPublished - Sep 2013

Fingerprint

Stents
Carotid Arteries
Carotid Stenosis
Pathologic Constriction
Arteries

Keywords

  • 3D-CT
  • Carotid artery stenting
  • Carotid stenosis
  • Plaque MRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Cite this

Novel 3D-CT evaluation of carotid stent volume : Greater chronological expansion of stents in patients with vulnerable plaques. / Itami, Hisakazu; Tokunaga, Koji; Okuma, Yu; Hishikawa, Tomohito; Sugiu, Kenji; Ida, Kentaro; Date, Isao.

In: Neuroradiology, Vol. 55, No. 9, 09.2013, p. 1153-1160.

Research output: Contribution to journalArticle

@article{4e3787b2abad4fb2b889f0eb9c278070,
title = "Novel 3D-CT evaluation of carotid stent volume: Greater chronological expansion of stents in patients with vulnerable plaques",
abstract = "Introduction: Although self-expanding carotid stents may dilate gradually, the degrees of residual stenosis have been quantified by the NASCET criteria, which is too simple to reflect the configuration of the stented artery. We measured the volumes of the stent lumens chronologically by 3D-CT in patients after carotid artery stenting (CAS), and analyzed the correlations between the volume change and medical factors. Methods: Fourteen patients with carotid artery stenosis were treated using self-expanding, open-cell stents. All patients underwent preoperative plaque MRI (magnetization-prepared rapid acquisition gradient-echo, MPRAGE) and chronological 3D-CT examinations of their stents immediately after their placement and 1 day, 1 week, and 1 month after the procedure. The volume of the stent lumen was measured using a 3D workstation. The correlations between stent volume and various factors including the presence of underlying diseases, plaque characteristics, and the results of the CAS procedure were analyzed. Results: Stent volume gradually increased in each case and had increased by 1.04-1.55 (mean, 1.25)-fold at 1 postoperative month. The presence of underlying medical diseases, plaque length, the degree of residual stenosis immediately after CAS, and plaque calcification did not have an impact on the change in stent volume. On the other hand, the stent volume increase was significantly larger in the patients with vulnerable plaques that demonstrated high MPRAGE signal intensity (P <0.05). Conclusions: A 3D-CT examination is useful for precisely measuring stent volume. Self-expanding stents in carotid arteries containing vulnerable plaques expand significantly more than those without such plaques in a follow-up period.",
keywords = "3D-CT, Carotid artery stenting, Carotid stenosis, Plaque MRI",
author = "Hisakazu Itami and Koji Tokunaga and Yu Okuma and Tomohito Hishikawa and Kenji Sugiu and Kentaro Ida and Isao Date",
year = "2013",
month = "9",
doi = "10.1007/s00234-013-1223-0",
language = "English",
volume = "55",
pages = "1153--1160",
journal = "Neuroradiology",
issn = "0028-3940",
publisher = "Springer Verlag",
number = "9",

}

TY - JOUR

T1 - Novel 3D-CT evaluation of carotid stent volume

T2 - Greater chronological expansion of stents in patients with vulnerable plaques

AU - Itami, Hisakazu

AU - Tokunaga, Koji

AU - Okuma, Yu

AU - Hishikawa, Tomohito

AU - Sugiu, Kenji

AU - Ida, Kentaro

AU - Date, Isao

PY - 2013/9

Y1 - 2013/9

N2 - Introduction: Although self-expanding carotid stents may dilate gradually, the degrees of residual stenosis have been quantified by the NASCET criteria, which is too simple to reflect the configuration of the stented artery. We measured the volumes of the stent lumens chronologically by 3D-CT in patients after carotid artery stenting (CAS), and analyzed the correlations between the volume change and medical factors. Methods: Fourteen patients with carotid artery stenosis were treated using self-expanding, open-cell stents. All patients underwent preoperative plaque MRI (magnetization-prepared rapid acquisition gradient-echo, MPRAGE) and chronological 3D-CT examinations of their stents immediately after their placement and 1 day, 1 week, and 1 month after the procedure. The volume of the stent lumen was measured using a 3D workstation. The correlations between stent volume and various factors including the presence of underlying diseases, plaque characteristics, and the results of the CAS procedure were analyzed. Results: Stent volume gradually increased in each case and had increased by 1.04-1.55 (mean, 1.25)-fold at 1 postoperative month. The presence of underlying medical diseases, plaque length, the degree of residual stenosis immediately after CAS, and plaque calcification did not have an impact on the change in stent volume. On the other hand, the stent volume increase was significantly larger in the patients with vulnerable plaques that demonstrated high MPRAGE signal intensity (P <0.05). Conclusions: A 3D-CT examination is useful for precisely measuring stent volume. Self-expanding stents in carotid arteries containing vulnerable plaques expand significantly more than those without such plaques in a follow-up period.

AB - Introduction: Although self-expanding carotid stents may dilate gradually, the degrees of residual stenosis have been quantified by the NASCET criteria, which is too simple to reflect the configuration of the stented artery. We measured the volumes of the stent lumens chronologically by 3D-CT in patients after carotid artery stenting (CAS), and analyzed the correlations between the volume change and medical factors. Methods: Fourteen patients with carotid artery stenosis were treated using self-expanding, open-cell stents. All patients underwent preoperative plaque MRI (magnetization-prepared rapid acquisition gradient-echo, MPRAGE) and chronological 3D-CT examinations of their stents immediately after their placement and 1 day, 1 week, and 1 month after the procedure. The volume of the stent lumen was measured using a 3D workstation. The correlations between stent volume and various factors including the presence of underlying diseases, plaque characteristics, and the results of the CAS procedure were analyzed. Results: Stent volume gradually increased in each case and had increased by 1.04-1.55 (mean, 1.25)-fold at 1 postoperative month. The presence of underlying medical diseases, plaque length, the degree of residual stenosis immediately after CAS, and plaque calcification did not have an impact on the change in stent volume. On the other hand, the stent volume increase was significantly larger in the patients with vulnerable plaques that demonstrated high MPRAGE signal intensity (P <0.05). Conclusions: A 3D-CT examination is useful for precisely measuring stent volume. Self-expanding stents in carotid arteries containing vulnerable plaques expand significantly more than those without such plaques in a follow-up period.

KW - 3D-CT

KW - Carotid artery stenting

KW - Carotid stenosis

KW - Plaque MRI

UR - http://www.scopus.com/inward/record.url?scp=84883877760&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84883877760&partnerID=8YFLogxK

U2 - 10.1007/s00234-013-1223-0

DO - 10.1007/s00234-013-1223-0

M3 - Article

C2 - 23821124

AN - SCOPUS:84883877760

VL - 55

SP - 1153

EP - 1160

JO - Neuroradiology

JF - Neuroradiology

SN - 0028-3940

IS - 9

ER -