Abstract
A, novel antimitotic compound named Nostodione A (Nd A) was isolated from a terrestrial blue-green alga Nostoc commune. Nostodione A disturbed the mitotic spindle formation of sea-urchin eggs and gave small spindles with low birefringence density. Nostodione, A. however, had no phytotoxicity on the germination of a dicotyledonous plant Medicago sativa. Based on the spectral analysis and chemical degradation, the structure of Nostodione A was elucidated.
| Original language | English |
|---|---|
| Pages (from-to) | 464-470 |
| Number of pages | 7 |
| Journal | Zeitschrift fur Naturforschung - Section C Journal of Biosciences |
| Volume | 49 |
| Issue number | 7-8 |
| DOIs | |
| Publication status | Published - Aug 1 1994 |
Keywords
- Blue-Green Alga
- Mitotic Spindle Poison
- Nostoc commune
- Nostodione, A
- Sea-Urchin Eggs
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
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Cite this
Kobayashi, A., Kaiiyama, S. I., Inawaka, K., Kanzaki, H., & Kawazu, K. (1994). Nostodione A, a Novel Mitotic Spindle Poison* from a Blue-Green Alga Nostoc commune. Zeitschrift fur Naturforschung - Section C Journal of Biosciences, 49(7-8), 464-470. https://doi.org/10.1515/znc-1994-7-812