Nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae elucidated by single-nucleotide variation analysis: a case investigation

Hideharu Hagiya, Kotaro Aoki, Yukihiro Akeda, Noriko Sakamoto, Norihisa Yamamoto, Hisao Yoshida, Isao Nishi, Yoshikazu Ishii, Kazunori Tomono

Research output: Contribution to journalArticle

1 Citation (Scopus)


Identifying transmission route of antimicrobial-resistant pathogen is essential for appropriate infection control strategy in healthcare facilities. We report the utility of single-nucleotide variation analysis in tracing nosocomial transmission of antimicrobial-resistant pathogens by describing a pseudo-outbreak case of carbapenem-resistant Klebsiella pneumoniae. The present case highlights that infection control strategy should encompass pathological dissection rooms, neglected but potentially highly contaminated places in hospitals.

Original languageEnglish
Pages (from-to)221-225
Number of pages5
Issue number2
Publication statusPublished - Apr 1 2017
Externally publishedYes



  • Autopsy
  • Carbapenem-resistant Enterobacteriaceae
  • Nosocomial infection
  • Pathological dissection room
  • Whole-genome sequencing

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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