Nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae elucidated by single-nucleotide variation analysis: a case investigation

Hideharu Hagiya, Kotaro Aoki, Yukihiro Akeda, Noriko Sakamoto, Norihisa Yamamoto, Hisao Yoshida, Isao Nishi, Yoshikazu Ishii, Kazunori Tomono

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Identifying transmission route of antimicrobial-resistant pathogen is essential for appropriate infection control strategy in healthcare facilities. We report the utility of single-nucleotide variation analysis in tracing nosocomial transmission of antimicrobial-resistant pathogens by describing a pseudo-outbreak case of carbapenem-resistant Klebsiella pneumoniae. The present case highlights that infection control strategy should encompass pathological dissection rooms, neglected but potentially highly contaminated places in hospitals.

Original languageEnglish
Pages (from-to)221-225
Number of pages5
JournalInfection
Volume45
Issue number2
DOIs
Publication statusPublished - Apr 1 2017
Externally publishedYes

Fingerprint

Carbapenems
Klebsiella pneumoniae
Infection Control
Nucleotides
Disease Outbreaks
Dissection
Delivery of Health Care

Keywords

  • Autopsy
  • Carbapenem-resistant Enterobacteriaceae
  • Nosocomial infection
  • Pathological dissection room
  • Whole-genome sequencing

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae elucidated by single-nucleotide variation analysis : a case investigation. / Hagiya, Hideharu; Aoki, Kotaro; Akeda, Yukihiro; Sakamoto, Noriko; Yamamoto, Norihisa; Yoshida, Hisao; Nishi, Isao; Ishii, Yoshikazu; Tomono, Kazunori.

In: Infection, Vol. 45, No. 2, 01.04.2017, p. 221-225.

Research output: Contribution to journalArticle

Hagiya, Hideharu ; Aoki, Kotaro ; Akeda, Yukihiro ; Sakamoto, Noriko ; Yamamoto, Norihisa ; Yoshida, Hisao ; Nishi, Isao ; Ishii, Yoshikazu ; Tomono, Kazunori. / Nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae elucidated by single-nucleotide variation analysis : a case investigation. In: Infection. 2017 ; Vol. 45, No. 2. pp. 221-225.
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