Normal values of real-time 3-dimensional echocardiographic parameters in a healthy Japanese population: The JAMP-3D study

Shota Fukuda, Hiroyuki Watanabe, Masao Daimon, Yukio Abe, Akihiro Hirashiki, Kumiko Hirata, Hiroshi Itoh, Masumi Iwai-Takano, Katsuomi Iwakura, Chisato Izumi, Takayuki Hidaka, Toshinori Yuasa, Kazuya Murata, Satoshi Nakatani, Kazuaki Negishi, Kazuhiro Nishigami, Tomoko Nishikage, Takahiro Ota, Akihiro Hayashida, Konomi SakataNobuhiro Tanaka, Satoshi Yamada, Kazuhiro Yamamoto, Junichi Yoshikawa

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Abstract

Background: The recently developed real-time 3-dimensional echocardiography (RT3DE) is a promising imaging method to quantify cardiac chamber volumes and their functions in clinical practice. However, normal reference values of RT3DE parameters have not been fully investigated in a large, healthy Japanese population. Methods and Results: This study consisted of 410 healthy subjects aged from 20 to 69 years who had a RT3DE at one of the 23 collaborating institutions. All subjects had no history of cardiac disease and no risk factors. The mean values in men and women were as follows: 50±12 ml/m 2 and 46±9 ml/m 2 for left ventricular (LV) end-diastolic volume index, 19±5 ml/m 2 and 17±4 ml/m 2 for end-systolic volume index, 61±4% and 63±4% for ejection fraction, 64±12 g/m 2 and 56±11 g/m 2 for mass index, 23±6 ml/m 2 and 24±6 ml/m 2 for left atrial (LA) maximum volume index, 10±3 ml/m 2 and 10±3 ml/m 2 for minimum volume index, and 58±6% and 58±6% for percent volume change. LV sizes decreased with age, whereas LV mass index did not change. LA sizes slightly increased with age. Conclusions: This multicenter investigation determined normal reference values for LV and LA sizes, and their functional parameters on RT3DE in a large, healthy Japanese population. The results of the present study support the use of RT3DE for the diagnosis and management of cardiovascular disease.

Original languageEnglish
Pages (from-to)1177-1181
Number of pages5
JournalCirculation Journal
Volume76
Issue number5
DOIs
Publication statusPublished - 2012

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Echocardiography
Reference Values
Population
Cardiac Volume
Stroke Volume
Heart Diseases
Healthy Volunteers
Cardiovascular Diseases

Keywords

  • Echocardiography
  • Japanese
  • Population

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Fukuda, S., Watanabe, H., Daimon, M., Abe, Y., Hirashiki, A., Hirata, K., ... Yoshikawa, J. (2012). Normal values of real-time 3-dimensional echocardiographic parameters in a healthy Japanese population: The JAMP-3D study. Circulation Journal, 76(5), 1177-1181. https://doi.org/10.1253/circj.CJ-11-1256

Normal values of real-time 3-dimensional echocardiographic parameters in a healthy Japanese population : The JAMP-3D study. / Fukuda, Shota; Watanabe, Hiroyuki; Daimon, Masao; Abe, Yukio; Hirashiki, Akihiro; Hirata, Kumiko; Itoh, Hiroshi; Iwai-Takano, Masumi; Iwakura, Katsuomi; Izumi, Chisato; Hidaka, Takayuki; Yuasa, Toshinori; Murata, Kazuya; Nakatani, Satoshi; Negishi, Kazuaki; Nishigami, Kazuhiro; Nishikage, Tomoko; Ota, Takahiro; Hayashida, Akihiro; Sakata, Konomi; Tanaka, Nobuhiro; Yamada, Satoshi; Yamamoto, Kazuhiro; Yoshikawa, Junichi.

In: Circulation Journal, Vol. 76, No. 5, 2012, p. 1177-1181.

Research output: Contribution to journalArticle

Fukuda, S, Watanabe, H, Daimon, M, Abe, Y, Hirashiki, A, Hirata, K, Itoh, H, Iwai-Takano, M, Iwakura, K, Izumi, C, Hidaka, T, Yuasa, T, Murata, K, Nakatani, S, Negishi, K, Nishigami, K, Nishikage, T, Ota, T, Hayashida, A, Sakata, K, Tanaka, N, Yamada, S, Yamamoto, K & Yoshikawa, J 2012, 'Normal values of real-time 3-dimensional echocardiographic parameters in a healthy Japanese population: The JAMP-3D study', Circulation Journal, vol. 76, no. 5, pp. 1177-1181. https://doi.org/10.1253/circj.CJ-11-1256
Fukuda, Shota ; Watanabe, Hiroyuki ; Daimon, Masao ; Abe, Yukio ; Hirashiki, Akihiro ; Hirata, Kumiko ; Itoh, Hiroshi ; Iwai-Takano, Masumi ; Iwakura, Katsuomi ; Izumi, Chisato ; Hidaka, Takayuki ; Yuasa, Toshinori ; Murata, Kazuya ; Nakatani, Satoshi ; Negishi, Kazuaki ; Nishigami, Kazuhiro ; Nishikage, Tomoko ; Ota, Takahiro ; Hayashida, Akihiro ; Sakata, Konomi ; Tanaka, Nobuhiro ; Yamada, Satoshi ; Yamamoto, Kazuhiro ; Yoshikawa, Junichi. / Normal values of real-time 3-dimensional echocardiographic parameters in a healthy Japanese population : The JAMP-3D study. In: Circulation Journal. 2012 ; Vol. 76, No. 5. pp. 1177-1181.
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AU - Fukuda, Shota

AU - Watanabe, Hiroyuki

AU - Daimon, Masao

AU - Abe, Yukio

AU - Hirashiki, Akihiro

AU - Hirata, Kumiko

AU - Itoh, Hiroshi

AU - Iwai-Takano, Masumi

AU - Iwakura, Katsuomi

AU - Izumi, Chisato

AU - Hidaka, Takayuki

AU - Yuasa, Toshinori

AU - Murata, Kazuya

AU - Nakatani, Satoshi

AU - Negishi, Kazuaki

AU - Nishigami, Kazuhiro

AU - Nishikage, Tomoko

AU - Ota, Takahiro

AU - Hayashida, Akihiro

AU - Sakata, Konomi

AU - Tanaka, Nobuhiro

AU - Yamada, Satoshi

AU - Yamamoto, Kazuhiro

AU - Yoshikawa, Junichi

PY - 2012

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N2 - Background: The recently developed real-time 3-dimensional echocardiography (RT3DE) is a promising imaging method to quantify cardiac chamber volumes and their functions in clinical practice. However, normal reference values of RT3DE parameters have not been fully investigated in a large, healthy Japanese population. Methods and Results: This study consisted of 410 healthy subjects aged from 20 to 69 years who had a RT3DE at one of the 23 collaborating institutions. All subjects had no history of cardiac disease and no risk factors. The mean values in men and women were as follows: 50±12 ml/m 2 and 46±9 ml/m 2 for left ventricular (LV) end-diastolic volume index, 19±5 ml/m 2 and 17±4 ml/m 2 for end-systolic volume index, 61±4% and 63±4% for ejection fraction, 64±12 g/m 2 and 56±11 g/m 2 for mass index, 23±6 ml/m 2 and 24±6 ml/m 2 for left atrial (LA) maximum volume index, 10±3 ml/m 2 and 10±3 ml/m 2 for minimum volume index, and 58±6% and 58±6% for percent volume change. LV sizes decreased with age, whereas LV mass index did not change. LA sizes slightly increased with age. Conclusions: This multicenter investigation determined normal reference values for LV and LA sizes, and their functional parameters on RT3DE in a large, healthy Japanese population. The results of the present study support the use of RT3DE for the diagnosis and management of cardiovascular disease.

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