Nonprevention of post-endoscopic retrograde cholangiopancreatographic pancreatitis by pancreatic stent after aspiration of pure pancreatic juice in patients with intraductal papillary mucinous neoplasms of the pancreas

Ryo Harada, Hirofumi Kawamoto, Hirotoshi Fukatsu, Hironari Katou, Ken Hirao, Naoko Kurihara, Osamu Mizuno, Tsuneyoshi Ogawa, Etsuji Ishida, Hiroyuki Okada, Kazuhide Yamamoto, Hiroshi Yamamoto

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objectives: The objective of this study was to evaluate the efficacy of a pancreatic stent regarding the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis after aspiration of pure pancreatic juice in patients with intraductal papillary mucinous neoplasms. Methods: A retrospective study was made to assess the outcome in 121 consecutive patients with intraductal papillary mucinous neoplasms who underwent endoscopic aspiration of pure pancreatic juice for cytologic examination between July 2001 and October 2007. From July 2001 to March 2004, 58 patients did not undergo pancreatic stent insertion (the no-stent [nS] group). The remaining 63 patients did undergo stent insertion (stent [S] group). Results: The overall incidences of post-ERCP pancreatitis was 11 (9.1%). The incidences of post-ERCP pancreatitis in the S and nS groups were 8 (12.7%) and 3 (5.2%; P = 0.21), respectively. In the male patients and the patients with a smaller diameter of the main pancreatic ducts, post-ERCP pancreatitis was seen more frequently in those in the S group (13% and 21%, respectively) than in those in the nS group (0% and 0%, respectively; P = 0.04, 0.03). Conclusions: The pancreatic stent did not seem to decrease the incidence of post-ERCP pancreatitis in patients with intraductal papillary mucinous neoplasms. Furthermore, the pancreatic stent seems to be potentially detrimental in male patients and in patients with small-diameter main pancreatic ducts.

Original languageEnglish
Pages (from-to)340-344
Number of pages5
JournalPancreas
Volume39
Issue number3
DOIs
Publication statusPublished - Apr 2010

Fingerprint

Pancreatic Juice
Pancreatic Neoplasms
Pancreatitis
Stents
Endoscopic Retrograde Cholangiopancreatography
Pancreatic Ducts
Incidence
Neoplasms
Retrospective Studies

Keywords

  • Aspiration of pure pancreatic juice
  • Intraductal papillary mucinous neoplasms (IPMNs)
  • Pancreatic stent
  • Post-ERCP pancreatitis

ASJC Scopus subject areas

  • Hepatology
  • Internal Medicine
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Nonprevention of post-endoscopic retrograde cholangiopancreatographic pancreatitis by pancreatic stent after aspiration of pure pancreatic juice in patients with intraductal papillary mucinous neoplasms of the pancreas. / Harada, Ryo; Kawamoto, Hirofumi; Fukatsu, Hirotoshi; Katou, Hironari; Hirao, Ken; Kurihara, Naoko; Mizuno, Osamu; Ogawa, Tsuneyoshi; Ishida, Etsuji; Okada, Hiroyuki; Yamamoto, Kazuhide; Yamamoto, Hiroshi.

In: Pancreas, Vol. 39, No. 3, 04.2010, p. 340-344.

Research output: Contribution to journalArticle

Harada, Ryo ; Kawamoto, Hirofumi ; Fukatsu, Hirotoshi ; Katou, Hironari ; Hirao, Ken ; Kurihara, Naoko ; Mizuno, Osamu ; Ogawa, Tsuneyoshi ; Ishida, Etsuji ; Okada, Hiroyuki ; Yamamoto, Kazuhide ; Yamamoto, Hiroshi. / Nonprevention of post-endoscopic retrograde cholangiopancreatographic pancreatitis by pancreatic stent after aspiration of pure pancreatic juice in patients with intraductal papillary mucinous neoplasms of the pancreas. In: Pancreas. 2010 ; Vol. 39, No. 3. pp. 340-344.
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abstract = "Objectives: The objective of this study was to evaluate the efficacy of a pancreatic stent regarding the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis after aspiration of pure pancreatic juice in patients with intraductal papillary mucinous neoplasms. Methods: A retrospective study was made to assess the outcome in 121 consecutive patients with intraductal papillary mucinous neoplasms who underwent endoscopic aspiration of pure pancreatic juice for cytologic examination between July 2001 and October 2007. From July 2001 to March 2004, 58 patients did not undergo pancreatic stent insertion (the no-stent [nS] group). The remaining 63 patients did undergo stent insertion (stent [S] group). Results: The overall incidences of post-ERCP pancreatitis was 11 (9.1{\%}). The incidences of post-ERCP pancreatitis in the S and nS groups were 8 (12.7{\%}) and 3 (5.2{\%}; P = 0.21), respectively. In the male patients and the patients with a smaller diameter of the main pancreatic ducts, post-ERCP pancreatitis was seen more frequently in those in the S group (13{\%} and 21{\%}, respectively) than in those in the nS group (0{\%} and 0{\%}, respectively; P = 0.04, 0.03). Conclusions: The pancreatic stent did not seem to decrease the incidence of post-ERCP pancreatitis in patients with intraductal papillary mucinous neoplasms. Furthermore, the pancreatic stent seems to be potentially detrimental in male patients and in patients with small-diameter main pancreatic ducts.",
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T1 - Nonprevention of post-endoscopic retrograde cholangiopancreatographic pancreatitis by pancreatic stent after aspiration of pure pancreatic juice in patients with intraductal papillary mucinous neoplasms of the pancreas

AU - Harada, Ryo

AU - Kawamoto, Hirofumi

AU - Fukatsu, Hirotoshi

AU - Katou, Hironari

AU - Hirao, Ken

AU - Kurihara, Naoko

AU - Mizuno, Osamu

AU - Ogawa, Tsuneyoshi

AU - Ishida, Etsuji

AU - Okada, Hiroyuki

AU - Yamamoto, Kazuhide

AU - Yamamoto, Hiroshi

PY - 2010/4

Y1 - 2010/4

N2 - Objectives: The objective of this study was to evaluate the efficacy of a pancreatic stent regarding the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis after aspiration of pure pancreatic juice in patients with intraductal papillary mucinous neoplasms. Methods: A retrospective study was made to assess the outcome in 121 consecutive patients with intraductal papillary mucinous neoplasms who underwent endoscopic aspiration of pure pancreatic juice for cytologic examination between July 2001 and October 2007. From July 2001 to March 2004, 58 patients did not undergo pancreatic stent insertion (the no-stent [nS] group). The remaining 63 patients did undergo stent insertion (stent [S] group). Results: The overall incidences of post-ERCP pancreatitis was 11 (9.1%). The incidences of post-ERCP pancreatitis in the S and nS groups were 8 (12.7%) and 3 (5.2%; P = 0.21), respectively. In the male patients and the patients with a smaller diameter of the main pancreatic ducts, post-ERCP pancreatitis was seen more frequently in those in the S group (13% and 21%, respectively) than in those in the nS group (0% and 0%, respectively; P = 0.04, 0.03). Conclusions: The pancreatic stent did not seem to decrease the incidence of post-ERCP pancreatitis in patients with intraductal papillary mucinous neoplasms. Furthermore, the pancreatic stent seems to be potentially detrimental in male patients and in patients with small-diameter main pancreatic ducts.

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KW - Aspiration of pure pancreatic juice

KW - Intraductal papillary mucinous neoplasms (IPMNs)

KW - Pancreatic stent

KW - Post-ERCP pancreatitis

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