Nonparaneoplastic limbic encephalitis with relapsing polychondritis

Yasuyuki Ohta, Isao Nagano, Daigo Niiya, Hideki Fujioka, Takumi Kishimoto, Mikio Shoji, Koji Abe

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Relapsing polychondritis (RP), which shows pain, swelling and destruction of the affected parts, is a rare autoimmune disorder affecting cartilage. We report a patient with RP that affected skull cartilage, who subsequently developed multifocal meningoencephalitis. The patient presented with severe recent memory disturbance, anxiety and moderate depression. MRI study showed bilateral median temporal lobe lesions including hippocampi and amygdaloidal bodies, abnormal findings that disappeared after treatment with high-dose steroids. This is thought to be the first case of RP presenting amnesic syndrome and mental disorder associated with nonparaneoplastic limbic encephalitis involving bilateral hippocampi and amygdaloidal bodies detected by MRI.

Original languageEnglish
Pages (from-to)85-88
Number of pages4
JournalJournal of the neurological sciences
Volume220
Issue number1-2
DOIs
Publication statusPublished - May 15 2004

Keywords

  • Amnesic syndrome
  • Connective tissue disease
  • Limbic encephalitis
  • MRI
  • Meningoencephalitis
  • Relapsing polychondritis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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