Autonomic nervous dysfunction, an inherent feature in patients who have heart failure, plays an important role in the initiation and progression of left ventricular dysfunction. Recent advances in medication have improved prognosis. Risk stratification in heart failure patients is very important in maximizing the benefit of these therapies. Plasma levels of neurohormonal factors such as norepinephrine and brain natriuretic peptide are reported as prognostic indicators in heart failure. However, they seem limited in describing local cardiac autonomic abnormalities and patients' prognoses by themselves. This article reviews nuclear cardiology techniques for imaging of autonomic innervation and discusses the clinical information available regarding their prognostic value in heart failure patients.
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine