Nonimmersive virtual reality mirror visual feedback therapy and its application for the treatment of complex regional pain syndrome: An open-label pilot study

Kenji Sato, Satoshi Fukumori, Takashi Matsusaki, Tomoko Maruo, Shinichi Ishikawa, Hiroyuki Nishie, Ken Takata, Hiroaki Mizuhara, Satoshi Mizobuchi, Hideki Nakatsuka, Masaki Matsumi, Akio Gofuku, Masataka Yokoyama, Kiyoshi Morita

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Objective: Chronic pain conditions such as phantom limb pain and complex regional pain syndrome are difficult to treat, and traditional pharmacological treatment and invasive neural block are not always effective. Plasticity in the central nervous system occurs in these conditions and may be associated with pain. Mirror visual feedback therapy aims to restore normal cortical organization and is applied in the treatment of chronic pain conditions. However, not all patients benefit from this treatment. Virtual reality technology is increasingly attracting attention for medical application, including as an analgesic modality. An advanced mirror visual feedback system with virtual reality technology may have increased analgesic efficacy and benefit a wider patient population. In this preliminary work, we developed a virtual reality mirror visual feedback system and applied it to the treatment of complex regional pain syndrome. Design: A small open-label case series. Five patients with complex regional pain syndrome received virtual reality mirror visual feedback therapy once a week for five to eight sessions on an outpatient basis. Patients were monitored for continued medication use and pain intensity. Results: Four of the five patients showed >50% reduction in pain intensity. Two of these patients ended their visits to our pain clinic after five sessions. Conclusion: Our results indicate that virtual reality mirror visual feedback therapy is a promising alternative treatment for complex regional pain syndrome. Further studies are necessary before concluding that analgesia provided from virtual reality mirror visual feedback therapy is the result of reversing maladaptive changes in pain perception.

Original languageEnglish
Pages (from-to)622-629
Number of pages8
JournalPain Medicine
Volume11
Issue number4
DOIs
Publication statusPublished - Apr 2010

Keywords

  • Complex Regional Pain Syndrome
  • Neuronal Plasticity
  • Pain
  • Virtual Reality

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine

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    Sato, K., Fukumori, S., Matsusaki, T., Maruo, T., Ishikawa, S., Nishie, H., Takata, K., Mizuhara, H., Mizobuchi, S., Nakatsuka, H., Matsumi, M., Gofuku, A., Yokoyama, M., & Morita, K. (2010). Nonimmersive virtual reality mirror visual feedback therapy and its application for the treatment of complex regional pain syndrome: An open-label pilot study. Pain Medicine, 11(4), 622-629. https://doi.org/10.1111/j.1526-4637.2010.00819.x