Vibrio vulnificus hemolysin (VVH) and streptolysin O (SLO) are both cholesterol-binding hemolysins. Both hemolysins were inactivated with H2O2, but the lost activity of SLO was restored by addition of thiol compounds, whereas that of VVH was not. Moreover, the activity of VVH was lowered by thiol compounds but not by thiolblocking agents, whereas the latter produced a decrease in SLO activity. These results suggest that VVH is not a thiol-activated hemolysin, in spite of its cholesterol-binding property.
|Number of pages||4|
|Journal||FEMS Microbiology Letters|
|Publication status||Published - 1985|
- Marine vibrio
- oxygen-labile hemolysin
ASJC Scopus subject areas
- Molecular Biology