Nitric oxide metabolites and adrenomedullin in human breast milk

Naoko Ohta, Hirokazu Tsukahara, Yusei Ohshima, Manabu Nishii, Yasuyo Ogawa, Kyouichi Sekine, Kenkou Kasuga, Mitsufumi Mayumi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

We found high concentrations of nitrite/nitrate (166-1460 μmol/l) in 43 milk samples obtained from 32 women during postpartum days 1-8, which indicates enhanced mammary nitric oxide (NO) secretion. We detected adrenomedullin (AM) (2.7-20.7 pmol/l) only in 9 of the 43 samples using highly specific immunoradiometric assay. It is uncertain whether the entire adrenomedullin is actively secreted in human milk.

Original languageEnglish
Pages (from-to)61-65
Number of pages5
JournalEarly Human Development
Volume78
Issue number1
DOIs
Publication statusPublished - Jun 2004
Externally publishedYes

Fingerprint

Adrenomedullin
Human Milk
Nitric Oxide
Immunoradiometric Assay
Nitrites
Nitrates
Postpartum Period
Milk
Breast

Keywords

  • Adrenomedullin
  • Human milk
  • Nitric oxide

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Nitric oxide metabolites and adrenomedullin in human breast milk. / Ohta, Naoko; Tsukahara, Hirokazu; Ohshima, Yusei; Nishii, Manabu; Ogawa, Yasuyo; Sekine, Kyouichi; Kasuga, Kenkou; Mayumi, Mitsufumi.

In: Early Human Development, Vol. 78, No. 1, 06.2004, p. 61-65.

Research output: Contribution to journalArticle

Ohta, N, Tsukahara, H, Ohshima, Y, Nishii, M, Ogawa, Y, Sekine, K, Kasuga, K & Mayumi, M 2004, 'Nitric oxide metabolites and adrenomedullin in human breast milk', Early Human Development, vol. 78, no. 1, pp. 61-65. https://doi.org/10.1016/j.earlhumdev.2004.04.002
Ohta, Naoko ; Tsukahara, Hirokazu ; Ohshima, Yusei ; Nishii, Manabu ; Ogawa, Yasuyo ; Sekine, Kyouichi ; Kasuga, Kenkou ; Mayumi, Mitsufumi. / Nitric oxide metabolites and adrenomedullin in human breast milk. In: Early Human Development. 2004 ; Vol. 78, No. 1. pp. 61-65.
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