Nitric oxide metabolites and adrenomedullin in human breast milk

Naoko Ohta, Hirokazu Tsukahara, Yusei Ohshima, Manabu Nishii, Yasuyo Ogawa, Kyouichi Sekine, Kenkou Kasuga, Mitsufumi Mayumi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

We found high concentrations of nitrite/nitrate (166-1460 μmol/l) in 43 milk samples obtained from 32 women during postpartum days 1-8, which indicates enhanced mammary nitric oxide (NO) secretion. We detected adrenomedullin (AM) (2.7-20.7 pmol/l) only in 9 of the 43 samples using highly specific immunoradiometric assay. It is uncertain whether the entire adrenomedullin is actively secreted in human milk.

Original languageEnglish
Pages (from-to)61-65
Number of pages5
JournalEarly Human Development
Volume78
Issue number1
DOIs
Publication statusPublished - Jun 1 2004
Externally publishedYes

Keywords

  • Adrenomedullin
  • Human milk
  • Nitric oxide

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

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  • Cite this

    Ohta, N., Tsukahara, H., Ohshima, Y., Nishii, M., Ogawa, Y., Sekine, K., Kasuga, K., & Mayumi, M. (2004). Nitric oxide metabolites and adrenomedullin in human breast milk. Early Human Development, 78(1), 61-65. https://doi.org/10.1016/j.earlhumdev.2004.04.002