NIRS measurement of hemodynamic evoked responses in the primary sensorimotor cortex

Mingdi Xu, Hirotsugu Takata, Sheng Ge, Takehito Hayami, Takao Yamasaki, Shozo Tobimatsu, Keiji Iramina

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Abstract

To investigate the relationship between neuronal activity and hemodynamics, we carried out a near-infrared spectroscopy (NIRS) study to measure the regional changes of hemoglobin concentration associated with cortical activation in the human sensorimotor cortex (SMI) to both voluntary and nonvoluntary tasks. We measured the hemodynamic evoked responses to voluntary finger movement and nonvoluntary electrical stimulation applied on the Angers (thumb and ring finger, respectively). Measurements were performed on 6 healthy right-handed volunteers using block paradigms and we analyzed both the spatial/temporal features and the magnitude of the optical signal induced by cerebral activation during these protocols. We constantly observed an increase in the cerebral concentration of oxygenated hemoglobin at the cortical side contralateral to the stimulated side. Our findings are in agreement with results in positron emission tomography (PET), functional magnetic resonance imaging (fMRI) and EEG (Electroencephalogram).

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages2492-2495
Number of pages4
DOIs
Publication statusPublished - 2007
Externally publishedYes
Event29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France
Duration: Aug 23 2007Aug 26 2007

Other

Other29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
CountryFrance
CityLyon
Period8/23/078/26/07

Fingerprint

Near infrared spectroscopy
Hemoglobin
Hemodynamics
Chemical activation
Positron emission tomography
Electroencephalography
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Xu, M., Takata, H., Ge, S., Hayami, T., Yamasaki, T., Tobimatsu, S., & Iramina, K. (2007). NIRS measurement of hemodynamic evoked responses in the primary sensorimotor cortex. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (pp. 2492-2495). [4352834] https://doi.org/10.1109/IEMBS.2007.4352834

NIRS measurement of hemodynamic evoked responses in the primary sensorimotor cortex. / Xu, Mingdi; Takata, Hirotsugu; Ge, Sheng; Hayami, Takehito; Yamasaki, Takao; Tobimatsu, Shozo; Iramina, Keiji.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2007. p. 2492-2495 4352834.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Xu, M, Takata, H, Ge, S, Hayami, T, Yamasaki, T, Tobimatsu, S & Iramina, K 2007, NIRS measurement of hemodynamic evoked responses in the primary sensorimotor cortex. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings., 4352834, pp. 2492-2495, 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07, Lyon, France, 8/23/07. https://doi.org/10.1109/IEMBS.2007.4352834
Xu M, Takata H, Ge S, Hayami T, Yamasaki T, Tobimatsu S et al. NIRS measurement of hemodynamic evoked responses in the primary sensorimotor cortex. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2007. p. 2492-2495. 4352834 https://doi.org/10.1109/IEMBS.2007.4352834
Xu, Mingdi ; Takata, Hirotsugu ; Ge, Sheng ; Hayami, Takehito ; Yamasaki, Takao ; Tobimatsu, Shozo ; Iramina, Keiji. / NIRS measurement of hemodynamic evoked responses in the primary sensorimotor cortex. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2007. pp. 2492-2495
@inproceedings{297fde5607f14871a2ce7214851e571c,
title = "NIRS measurement of hemodynamic evoked responses in the primary sensorimotor cortex",
abstract = "To investigate the relationship between neuronal activity and hemodynamics, we carried out a near-infrared spectroscopy (NIRS) study to measure the regional changes of hemoglobin concentration associated with cortical activation in the human sensorimotor cortex (SMI) to both voluntary and nonvoluntary tasks. We measured the hemodynamic evoked responses to voluntary finger movement and nonvoluntary electrical stimulation applied on the Angers (thumb and ring finger, respectively). Measurements were performed on 6 healthy right-handed volunteers using block paradigms and we analyzed both the spatial/temporal features and the magnitude of the optical signal induced by cerebral activation during these protocols. We constantly observed an increase in the cerebral concentration of oxygenated hemoglobin at the cortical side contralateral to the stimulated side. Our findings are in agreement with results in positron emission tomography (PET), functional magnetic resonance imaging (fMRI) and EEG (Electroencephalogram).",
author = "Mingdi Xu and Hirotsugu Takata and Sheng Ge and Takehito Hayami and Takao Yamasaki and Shozo Tobimatsu and Keiji Iramina",
year = "2007",
doi = "10.1109/IEMBS.2007.4352834",
language = "English",
isbn = "1424407885",
pages = "2492--2495",
booktitle = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",

}

TY - GEN

T1 - NIRS measurement of hemodynamic evoked responses in the primary sensorimotor cortex

AU - Xu, Mingdi

AU - Takata, Hirotsugu

AU - Ge, Sheng

AU - Hayami, Takehito

AU - Yamasaki, Takao

AU - Tobimatsu, Shozo

AU - Iramina, Keiji

PY - 2007

Y1 - 2007

N2 - To investigate the relationship between neuronal activity and hemodynamics, we carried out a near-infrared spectroscopy (NIRS) study to measure the regional changes of hemoglobin concentration associated with cortical activation in the human sensorimotor cortex (SMI) to both voluntary and nonvoluntary tasks. We measured the hemodynamic evoked responses to voluntary finger movement and nonvoluntary electrical stimulation applied on the Angers (thumb and ring finger, respectively). Measurements were performed on 6 healthy right-handed volunteers using block paradigms and we analyzed both the spatial/temporal features and the magnitude of the optical signal induced by cerebral activation during these protocols. We constantly observed an increase in the cerebral concentration of oxygenated hemoglobin at the cortical side contralateral to the stimulated side. Our findings are in agreement with results in positron emission tomography (PET), functional magnetic resonance imaging (fMRI) and EEG (Electroencephalogram).

AB - To investigate the relationship between neuronal activity and hemodynamics, we carried out a near-infrared spectroscopy (NIRS) study to measure the regional changes of hemoglobin concentration associated with cortical activation in the human sensorimotor cortex (SMI) to both voluntary and nonvoluntary tasks. We measured the hemodynamic evoked responses to voluntary finger movement and nonvoluntary electrical stimulation applied on the Angers (thumb and ring finger, respectively). Measurements were performed on 6 healthy right-handed volunteers using block paradigms and we analyzed both the spatial/temporal features and the magnitude of the optical signal induced by cerebral activation during these protocols. We constantly observed an increase in the cerebral concentration of oxygenated hemoglobin at the cortical side contralateral to the stimulated side. Our findings are in agreement with results in positron emission tomography (PET), functional magnetic resonance imaging (fMRI) and EEG (Electroencephalogram).

UR - http://www.scopus.com/inward/record.url?scp=57649142813&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=57649142813&partnerID=8YFLogxK

U2 - 10.1109/IEMBS.2007.4352834

DO - 10.1109/IEMBS.2007.4352834

M3 - Conference contribution

C2 - 18002500

AN - SCOPUS:57649142813

SN - 1424407885

SN - 9781424407880

SP - 2492

EP - 2495

BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

ER -