NIRS measurement of hemodynamic evoked responses in the primary somatosensory cortex by finger stimulation

Mingdi Xu, Hirotsugu Takata, Sheng Ge, Takehito Hayami, Takao Yamasaki, Shozo Tobimatsu, Keiji Iramina

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

To investigate the relationship between neuronal activity and hemodynamics, we carried out an NIRS study (near-infrared spectroscopy) to measure the regional changes of hemoglobin concentration associated with cortical activation in the primary somatosensory cortex (SI) to electrical stimuli. We examined the hemodynamic evoked responses to the electrical stimuli applied on the fingers (right thumb and ring finger, respectively). NIRS measurements were performed on 6 healthy right-handed volunteers using block paradigms and we analyzed both the spatial/temporal features and the magnitude of the optical signal induced by cerebral activation during these paradigms. Based on the experiment data, we consistently found an increase/decrease in the cerebral concentration of oxygenated hemoglobin [oxy-Hb]/deoxygenated hemoglobin [deoxy-Hb] at the cortical side contralateral to the stimulated side. Firstly, we found that, using NIRS, we can distinguish the local distribution of fingers on SI, whose result is in good accordance with the anatomical arrangement of hand area in SI. Secondly, we investigated the effects of electrical stimuli intensity on the hemodynamic evoked responses in SI. We found that, after raising the electrical stimuli intensity, an obvious increment of [oxy-Hb] in SI can be observed. Our findings based on NIRS optical imaging are in agreement with results in positron emission tomography (FET), functional magnetic resonance imaging (fMRI) and EEG (Electroencephalogram).

Original languageEnglish
Title of host publication2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
Pages1425-1429
Number of pages5
DOIs
Publication statusPublished - 2007
Externally publishedYes
Event2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007 - Beijing, China
Duration: May 23 2007May 27 2007

Other

Other2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007
CountryChina
CityBeijing
Period5/23/075/27/07

Fingerprint

Somatosensory Cortex
Hemoglobin
Hemodynamics
Fingers
Hemoglobins
Chemical activation
Positron emission tomography
Near infrared spectroscopy
Near-Infrared Spectroscopy
Optical Imaging
Thumb
Field effect transistors
Electroencephalography
Positron-Emission Tomography
Volunteers
Hand
Magnetic Resonance Imaging
Imaging techniques
Experiments

Keywords

  • Electrical stimuli
  • Hemodynamic evoked responses
  • Near-infrared spectroscopy (NIRS)
  • Primary somatosensory cortex (SI)

ASJC Scopus subject areas

  • Biomedical Engineering
  • Medicine(all)

Cite this

Xu, M., Takata, H., Ge, S., Hayami, T., Yamasaki, T., Tobimatsu, S., & Iramina, K. (2007). NIRS measurement of hemodynamic evoked responses in the primary somatosensory cortex by finger stimulation. In 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007 (pp. 1425-1429). [4381980] https://doi.org/10.1109/ICCME.2007.4381980

NIRS measurement of hemodynamic evoked responses in the primary somatosensory cortex by finger stimulation. / Xu, Mingdi; Takata, Hirotsugu; Ge, Sheng; Hayami, Takehito; Yamasaki, Takao; Tobimatsu, Shozo; Iramina, Keiji.

2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007. 2007. p. 1425-1429 4381980.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Xu, M, Takata, H, Ge, S, Hayami, T, Yamasaki, T, Tobimatsu, S & Iramina, K 2007, NIRS measurement of hemodynamic evoked responses in the primary somatosensory cortex by finger stimulation. in 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007., 4381980, pp. 1425-1429, 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007, Beijing, China, 5/23/07. https://doi.org/10.1109/ICCME.2007.4381980
Xu M, Takata H, Ge S, Hayami T, Yamasaki T, Tobimatsu S et al. NIRS measurement of hemodynamic evoked responses in the primary somatosensory cortex by finger stimulation. In 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007. 2007. p. 1425-1429. 4381980 https://doi.org/10.1109/ICCME.2007.4381980
Xu, Mingdi ; Takata, Hirotsugu ; Ge, Sheng ; Hayami, Takehito ; Yamasaki, Takao ; Tobimatsu, Shozo ; Iramina, Keiji. / NIRS measurement of hemodynamic evoked responses in the primary somatosensory cortex by finger stimulation. 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007. 2007. pp. 1425-1429
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