Nicorandil abolished repolarisation alternans in a patient with idiopathic long QT syndrome.

Y. Fujimoto, Hiroshi Morita, K. K. Fukushima, T. Ohe

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Abstract

A 23 year old woman with idiopathic long QT syndrome had repeated syncopal attacks associated with torsades de pointes. T wave alternans (TWA) was recorded and the QT interval was abnormally prolonged during treadmill exercise test. Monophasic action potential (MAP) alternans also appeared after an abrupt shortening of the cycle length in electrophysiological study. After intravenous administration of nicorandil 6 mg, both TWA and MAP alternans disappeared.

Original languageEnglish
JournalHeart
Volume82
Issue number5
Publication statusPublished - 1999

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