Nicorandil abolished repolarisation alternans in a patient with idiopathic long QT syndrome.

Y. Fujimoto; H. Morita; K. K. Fukushima; T. Ohe

doi:10.1136/hrt.82.5.e8

Nicorandil abolished repolarisation alternans in a patient with idiopathic long QT syndrome.

Y. Fujimoto, H. Morita, K. K. Fukushima, T. Ohe

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

A 23 year old woman with idiopathic long QT syndrome had repeated syncopal attacks associated with torsades de pointes. T wave alternans (TWA) was recorded and the QT interval was abnormally prolonged during treadmill exercise test. Monophasic action potential (MAP) alternans also appeared after an abrupt shortening of the cycle length in electrophysiological study. After intravenous administration of nicorandil 6 mg, both TWA and MAP alternans disappeared.

Original language	English
Pages (from-to)	e8
Journal	Heart (British Cardiac Society)
Volume	82
Issue number	5
DOIs	https://doi.org/10.1136/hrt.82.5.e8
Publication status	Published - Nov 1999

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1136/hrt.82.5.e8

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title = "Nicorandil abolished repolarisation alternans in a patient with idiopathic long QT syndrome.",

abstract = "A 23 year old woman with idiopathic long QT syndrome had repeated syncopal attacks associated with torsades de pointes. T wave alternans (TWA) was recorded and the QT interval was abnormally prolonged during treadmill exercise test. Monophasic action potential (MAP) alternans also appeared after an abrupt shortening of the cycle length in electrophysiological study. After intravenous administration of nicorandil 6 mg, both TWA and MAP alternans disappeared.",

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AU - Fujimoto, Y.

AU - Morita, H.

AU - Fukushima, K. K.

AU - Ohe, T.

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AB - A 23 year old woman with idiopathic long QT syndrome had repeated syncopal attacks associated with torsades de pointes. T wave alternans (TWA) was recorded and the QT interval was abnormally prolonged during treadmill exercise test. Monophasic action potential (MAP) alternans also appeared after an abrupt shortening of the cycle length in electrophysiological study. After intravenous administration of nicorandil 6 mg, both TWA and MAP alternans disappeared.

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Nicorandil abolished repolarisation alternans in a patient with idiopathic long QT syndrome.

Abstract

ASJC Scopus subject areas

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