Nickel catalyzed imine aldol reactions between activated imines and pronucleophiles

Naomi Shida, Yasufumi Kubota, Hiroyuki Fukui, Naoki Asao, Isao Kadota, Yoshinori Yamamoto

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Treatment of activated imines 1 with carbonyl compounds 2 in the presence of catalytic amounts of NiCl2(PPh3)2 or NiBr2(PPh3)2 at room temperature affords imine aldol products 3 in high to good yields.

Original languageEnglish
Pages (from-to)5023-5026
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number28
DOIs
Publication statusPublished - Jul 10 1995
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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