Ni-catalyzed decarbonylative cyanation of acyl chlorides with trimethylsilyl cyanide has been achieved. This transformation is applicable to the synthesis of an array of nitrile compounds bearing a wide range of functional groups under neutral conditions. The step-by-step experimental studies revealed that the reaction sequences of the present catalytic reaction are oxidative addition, transmetalation, decarbonylation, and reductive elimination.
|Number of pages||6|
|Publication status||Published - Sept 6 2019|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry