New cytotoxic phenolic derivatives from matured fruits of magnolia denudata

Toshiro Noshita, Hiromasa Kiyota, Yumi Kidachi, Kazuo Ryoyama, Shinji Funayama, Ken Hanada, Tetsuya Murayama

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Magnolia species are widely cultivated in Japan as garden plants, and have been found to contain various compounds, including alkaloids, terpenoids, lignans, and neolignans. The constituents of the mature fruits of M. denudata were investigated, and two new phenolic derivatives, named denudalide and denudaquinol, were isolated and characterized, together with a known neolignan compound (denudatin A). Denudalide and denudaquinol showed cytotoxicity against the SFME and r/mHM-SFME-1 cell lines.

Original languageEnglish
Pages (from-to)726-728
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume73
Issue number3
DOIs
Publication statusPublished - 2009
Externally publishedYes

Fingerprint

Magnolia
Lignans
Fruits
Fruit
Derivatives
Terpenes
Cytotoxicity
Alkaloids
Japan
Cells
Cell Line

Keywords

  • Benzofuranone
  • Cytotoxic metabolite
  • Denudalide
  • Denudaquinol
  • Magnolia denudata

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Applied Microbiology and Biotechnology
  • Analytical Chemistry
  • Organic Chemistry

Cite this

Noshita, T., Kiyota, H., Kidachi, Y., Ryoyama, K., Funayama, S., Hanada, K., & Murayama, T. (2009). New cytotoxic phenolic derivatives from matured fruits of magnolia denudata. Bioscience, Biotechnology and Biochemistry, 73(3), 726-728. https://doi.org/10.1271/bbb.80597

New cytotoxic phenolic derivatives from matured fruits of magnolia denudata. / Noshita, Toshiro; Kiyota, Hiromasa; Kidachi, Yumi; Ryoyama, Kazuo; Funayama, Shinji; Hanada, Ken; Murayama, Tetsuya.

In: Bioscience, Biotechnology and Biochemistry, Vol. 73, No. 3, 2009, p. 726-728.

Research output: Contribution to journalArticle

Noshita, T, Kiyota, H, Kidachi, Y, Ryoyama, K, Funayama, S, Hanada, K & Murayama, T 2009, 'New cytotoxic phenolic derivatives from matured fruits of magnolia denudata', Bioscience, Biotechnology and Biochemistry, vol. 73, no. 3, pp. 726-728. https://doi.org/10.1271/bbb.80597
Noshita, Toshiro ; Kiyota, Hiromasa ; Kidachi, Yumi ; Ryoyama, Kazuo ; Funayama, Shinji ; Hanada, Ken ; Murayama, Tetsuya. / New cytotoxic phenolic derivatives from matured fruits of magnolia denudata. In: Bioscience, Biotechnology and Biochemistry. 2009 ; Vol. 73, No. 3. pp. 726-728.
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