New concept bioceramics composed of octacalcium phosphate (OCP) and dicarboxylic acid-intercalated OCP via hydrothermal hot-pressing

Shiho Ishihara, Takuya Matsumoto, Takamasa Onoki, Taiji Sohmura, Atsushi Nakahira

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Octacalcium phosphate (OCP) and adipic acid-intercalated complexed OCP (Adi-OCP) were synthesized. Moreover, we made ceramic bodies out of them through a hydrothermal hot-pressing (HHP) method. Characteristic features of both the powder and ceramics were investigated by the X-ray diffraction method (XRD). Surface morphology of the ceramics was observed by scanning electron microscopy (SEM). Density, compressive strength and pore size distribution of the ceramics were measured. Crystalline structure of the newly developed OCP ceramics had no phase transformation from the starting materials. Moreover, the newly developed OCP ceramics had good mechanical properties only through the HHP treatment with a temperature as low as 110 °C. In order to evaluate bioactivity, the ceramics were immersed in simulating body fluid (SBF). It was predicted that OCP and Adi-OCP had better bioactivity than that of conventional HAp ceramics.

Original languageEnglish
Pages (from-to)1885-1888
Number of pages4
JournalMaterials Science and Engineering C
Volume29
Issue number6
DOIs
Publication statusPublished - Aug 1 2009
Externally publishedYes

Keywords

  • Biomaterials
  • Organic/inorganic hybrid
  • Sustainable drug release

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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