New 6/8/6-taxanes isolated from the heartwood of taxus cuspidata

Kai Zhang, Yong Li, Zhi Yi Ni, Man Li Zhang, Yu Fang Wang, Qing Wen Shi, Chang Hong Huo, Françoise Sauriol, Hiromasa Kiyota, Yu Cheng Gu, Mei Dong

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Two new natural taxanes were isolated from the heartwood of Taxus cuspidata. The structures were established as rel-(2α,5α,7β, 9α,10β,12α)-7,9-bis(acetyloxy)-2-(benzoyloxy)-11,12-epoxy-1, 5-dihydroxy-10-[(hydroxyacetyl)oxy]tax-4(20)-en-13-one (1), and (2α,5α,10β,14β)-taxa-4(20),11-diene-2,5,10,14-tetrol 2-acetate (2) on the basis of spectroscopic analysis.

Original languageEnglish
Pages (from-to)1566-1572
Number of pages7
JournalHelvetica Chimica Acta
Volume95
Issue number9
DOIs
Publication statusPublished - Sep 1 2012
Externally publishedYes

Keywords

  • Taxanes
  • Taxus cuspidata

ASJC Scopus subject areas

  • Catalysis
  • Biochemistry
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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  • Cite this

    Zhang, K., Li, Y., Ni, Z. Y., Zhang, M. L., Wang, Y. F., Shi, Q. W., Huo, C. H., Sauriol, F., Kiyota, H., Gu, Y. C., & Dong, M. (2012). New 6/8/6-taxanes isolated from the heartwood of taxus cuspidata. Helvetica Chimica Acta, 95(9), 1566-1572. https://doi.org/10.1002/hlca.201200045