Neurohypophysial hormones regulate amphibious behaviour in the mudskipper goby

Tatsuya Sakamoto, Yudai Nishiyama, Aoi Ikeda, Hideya Takahashi, Susumu Hyodo, Nao Kagawa, Hirotaka Sakamoto

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The neurohypophysial hormones, arginine vasotocin and isotocin, regulate both hydromineral balance and social behaviors in fish. In the amphibious mudskipper, Periophthalmus modestus, we previously found arginine-vasotocin-specific regulation of aggressive behavior, including migration of the submissive subordinate into water. This migration also implies the need for adaptation to dehydration. Here, we examined the effects of arginine vasotocin and isotocin administration on the amphibious behavior of individual mudskippers in vivo. The mudskippers remained in the water for an increased period of time after 1-8 h of intracerebroventricular (ICV) injection with 500 pg/g arginine vasotocin or isotocin. The 'frequency of migration' was decreased after ICV injection of arginine vasotocin or isotocin, reflecting a tendency to remain in the water. ICV injections of isotocin receptor antagonist with arginine vasotocin or isotocin inhibited all of these hormonal effects. In animals kept out of water, mRNA expression of brain arginine vasotocin and isotocin precursors increased 3- and 1.5-fold, respectively. Given the relatively wide distribution of arginine vasotocin fibres throughout the mudskipper brain, induction of arginine vasotocin and isotocin under terrestrial conditions may be involved also in the preference for an aquatic habitat as ligands for brain isotocin receptors.

Original languageEnglish
Article numbere0134605
JournalPLoS One
Volume10
Issue number7
DOIs
Publication statusPublished - Jul 31 2015

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arginine vasotocin
Posterior Pituitary Hormones
Vasotocin
hormones
Brain
Water
injection
brain
Injections
water
isotocin
receptors
Social Behavior
aquatic habitat
Dehydration
social behavior
Fish
Ecosystem
aggression
antagonists

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Neurohypophysial hormones regulate amphibious behaviour in the mudskipper goby. / Sakamoto, Tatsuya; Nishiyama, Yudai; Ikeda, Aoi; Takahashi, Hideya; Hyodo, Susumu; Kagawa, Nao; Sakamoto, Hirotaka.

In: PLoS One, Vol. 10, No. 7, e0134605, 31.07.2015.

Research output: Contribution to journalArticle

Sakamoto T, Nishiyama Y, Ikeda A, Takahashi H, Hyodo S, Kagawa N et al. Neurohypophysial hormones regulate amphibious behaviour in the mudskipper goby. PLoS One. 2015 Jul 31;10(7). e0134605. https://doi.org/10.1371/journal.pone.0134605
Sakamoto, Tatsuya ; Nishiyama, Yudai ; Ikeda, Aoi ; Takahashi, Hideya ; Hyodo, Susumu ; Kagawa, Nao ; Sakamoto, Hirotaka. / Neurohypophysial hormones regulate amphibious behaviour in the mudskipper goby. In: PLoS One. 2015 ; Vol. 10, No. 7.
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