Abstract
Nemerteans (ribbon worms) and phoronids (horseshoe worms) are closely related lophotrochozoans - a group of animals including leeches, snails and other invertebrates. Lophotrochozoans represent a superphylum that is crucial to our understanding of bilaterian evolution. However, given the inconsistency of molecular and morphological data for these groups, their origins have been unclear. Here, we present draft genomes of the nemertean Notospermus geniculatus and the phoronid Phoronis australis, together with transcriptomes along the adult bodies. Our genome-based phylogenetic analyses place Nemertea sister to the group containing Phoronida and Brachiopoda. We show that lophotrochozoans share many gene families with deuterostomes, suggesting that these two groups retain a core bilaterian gene repertoire that ecdysozoans (for example, flies and nematodes) and platyzoans (for example, flatworms and rotifers) do not. Comparative transcriptomics demonstrates that lophophores of phoronids and brachiopods are similar not only morphologically, but also at the molecular level. Despite dissimilar head structures, lophophores express vertebrate head and neuronal marker genes. This finding suggests a common origin of bilaterian head patterning, although different heads evolved independently in each lineage. Furthermore, we observe lineage-specific expansions of innate immunity and toxin-related genes. Together, our study reveals a dual nature of lophotrochozoans, where conserved and lineage-specific features shape their evolution.
| Original language | English |
|---|---|
| Pages (from-to) | 141-151 |
| Number of pages | 11 |
| Journal | Nature Ecology and Evolution |
| Volume | 2 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1 2018 |
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ASJC Scopus subject areas
- Ecology, Evolution, Behavior and Systematics
- Ecology
Cite this
Nemertean and phoronid genomes reveal lophotrochozoan evolution and the origin of bilaterian heads. / Luo, Yi Jyun; Kanda, Miyuki; Koyanagi, Ryo; Hisata, Kanako; Akiyama, Tadashi; Sakamoto, Hirotaka; Sakamoto, Tatsuya; Satoh, Noriyuki.
In: Nature Ecology and Evolution, Vol. 2, No. 1, 01.01.2018, p. 141-151.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Nemertean and phoronid genomes reveal lophotrochozoan evolution and the origin of bilaterian heads
AU - Luo, Yi Jyun
AU - Kanda, Miyuki
AU - Koyanagi, Ryo
AU - Hisata, Kanako
AU - Akiyama, Tadashi
AU - Sakamoto, Hirotaka
AU - Sakamoto, Tatsuya
AU - Satoh, Noriyuki
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Nemerteans (ribbon worms) and phoronids (horseshoe worms) are closely related lophotrochozoans - a group of animals including leeches, snails and other invertebrates. Lophotrochozoans represent a superphylum that is crucial to our understanding of bilaterian evolution. However, given the inconsistency of molecular and morphological data for these groups, their origins have been unclear. Here, we present draft genomes of the nemertean Notospermus geniculatus and the phoronid Phoronis australis, together with transcriptomes along the adult bodies. Our genome-based phylogenetic analyses place Nemertea sister to the group containing Phoronida and Brachiopoda. We show that lophotrochozoans share many gene families with deuterostomes, suggesting that these two groups retain a core bilaterian gene repertoire that ecdysozoans (for example, flies and nematodes) and platyzoans (for example, flatworms and rotifers) do not. Comparative transcriptomics demonstrates that lophophores of phoronids and brachiopods are similar not only morphologically, but also at the molecular level. Despite dissimilar head structures, lophophores express vertebrate head and neuronal marker genes. This finding suggests a common origin of bilaterian head patterning, although different heads evolved independently in each lineage. Furthermore, we observe lineage-specific expansions of innate immunity and toxin-related genes. Together, our study reveals a dual nature of lophotrochozoans, where conserved and lineage-specific features shape their evolution.
AB - Nemerteans (ribbon worms) and phoronids (horseshoe worms) are closely related lophotrochozoans - a group of animals including leeches, snails and other invertebrates. Lophotrochozoans represent a superphylum that is crucial to our understanding of bilaterian evolution. However, given the inconsistency of molecular and morphological data for these groups, their origins have been unclear. Here, we present draft genomes of the nemertean Notospermus geniculatus and the phoronid Phoronis australis, together with transcriptomes along the adult bodies. Our genome-based phylogenetic analyses place Nemertea sister to the group containing Phoronida and Brachiopoda. We show that lophotrochozoans share many gene families with deuterostomes, suggesting that these two groups retain a core bilaterian gene repertoire that ecdysozoans (for example, flies and nematodes) and platyzoans (for example, flatworms and rotifers) do not. Comparative transcriptomics demonstrates that lophophores of phoronids and brachiopods are similar not only morphologically, but also at the molecular level. Despite dissimilar head structures, lophophores express vertebrate head and neuronal marker genes. This finding suggests a common origin of bilaterian head patterning, although different heads evolved independently in each lineage. Furthermore, we observe lineage-specific expansions of innate immunity and toxin-related genes. Together, our study reveals a dual nature of lophotrochozoans, where conserved and lineage-specific features shape their evolution.
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UR - http://www.scopus.com/inward/citedby.url?scp=85036547928&partnerID=8YFLogxK
U2 - 10.1038/s41559-017-0389-y
DO - 10.1038/s41559-017-0389-y
M3 - Article
C2 - 29203924
AN - SCOPUS:85036547928
VL - 2
SP - 141
EP - 151
JO - Nature Ecology and Evolution
JF - Nature Ecology and Evolution
SN - 2397-334X
IS - 1
ER -