Negishi alkyl-aryl cross-coupling catalyzed by Rh

Efficiency of novel tripodal 3-diphenylphosphino-2-(diphenylphosphino)methyl-2-methylpropyl acetate ligand

Syogo Ejiri, Shunsuke Odo, Hideki Takahashi, Yugo Nishimura, Kazuma Gotoh, Yasushi Nishihara, Kentaro Takagi

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

3-Diphenylphosphino-2-(diphenylphoshino)methyl-2-methylpropyl acetate acted as an efficient ligand for a Rh catalyst, achieving cross-coupling between arylzinc compounds bearing electron-withdrawing groups and alkyl electrophiles. The beneficial effect of the tripodal ligand and such aryl nucleophiles was discussed with regard to the specificity of the Rh catalysis.

Original languageEnglish
Pages (from-to)1692-1695
Number of pages4
JournalOrganic Letters
Volume12
Issue number8
DOIs
Publication statusPublished - Apr 16 2010

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cross coupling
acetates
Acetates
Bearings (structural)
Ligands
Nucleophiles
ligands
nucleophiles
Catalysis
catalysis
Electrons
catalysts
Catalysts
electrons

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Negishi alkyl-aryl cross-coupling catalyzed by Rh : Efficiency of novel tripodal 3-diphenylphosphino-2-(diphenylphosphino)methyl-2-methylpropyl acetate ligand. / Ejiri, Syogo; Odo, Shunsuke; Takahashi, Hideki; Nishimura, Yugo; Gotoh, Kazuma; Nishihara, Yasushi; Takagi, Kentaro.

In: Organic Letters, Vol. 12, No. 8, 16.04.2010, p. 1692-1695.

Research output: Contribution to journalArticle

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AU - Takagi, Kentaro

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