Abstract
Objective. We attempted to prospectively determine the role of magnetic resonance imaging (MRI) in very early cervical cancer. Study design. T2-weighted and T1-dynamic enhanced images from patients with invasive or noninvasive lesions of the cervix were reviewed by two radiologists who had no clinical information on these patients. At least 12 longitudinal sections prepared from the surgically removed cervix were reviewed by a pathologist. The correlation between MRI and histological findings was analyzed in terms of depth of invasion. Results. Seventy-nine cases were entered into the study and 75 were evaluable. Accuracy of T2 MR images for invasive and noninvasive disease by Radiologist 1 and Radiologist 2 was 0.8533 and 0.7733, respectively. Accuracy was greater (0.9867 and 0.9467, respectively) for the detection of noninvasive plus microinvasive lesions >5 mm vs invasive lesions ≤5 mm. Dynamic technique provided only limited additional value in the detection of microinvasive cervical carcinoma. Conclusion. Simple T2 MRI is useful in differentiating noninvasive or microinvasive cervical lesions from invasive cervical carcinoma of the cervix >5 mm. (C) 2000 Academic Press.
| Original language | English |
|---|---|
| Pages (from-to) | 451-456 |
| Number of pages | 6 |
| Journal | Gynecologic Oncology |
| Volume | 79 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2000 |
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Keywords
- Cervical carcinoma
- Dynamic enhancement
- Early stage
- Magnetic resonance imaging
ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Oncology
Cite this
Negative MRI findings with invasive cervical biopsy may indicate stage IA cervical carcinoma. / Fujiwara, Keiichi; Yoden, Eisaku; Asakawa, Toru; Shimizu, Michio; Hirokawa, Mitsuyoshi; Mikami, Yoshiki; Oda, Takashi; Joja, Ikuo; Imajo, Yoshinari; Kohno, Ichiro.
In: Gynecologic Oncology, Vol. 79, No. 3, 2000, p. 451-456.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Negative MRI findings with invasive cervical biopsy may indicate stage IA cervical carcinoma
AU - Fujiwara, Keiichi
AU - Yoden, Eisaku
AU - Asakawa, Toru
AU - Shimizu, Michio
AU - Hirokawa, Mitsuyoshi
AU - Mikami, Yoshiki
AU - Oda, Takashi
AU - Joja, Ikuo
AU - Imajo, Yoshinari
AU - Kohno, Ichiro
PY - 2000
Y1 - 2000
N2 - Objective. We attempted to prospectively determine the role of magnetic resonance imaging (MRI) in very early cervical cancer. Study design. T2-weighted and T1-dynamic enhanced images from patients with invasive or noninvasive lesions of the cervix were reviewed by two radiologists who had no clinical information on these patients. At least 12 longitudinal sections prepared from the surgically removed cervix were reviewed by a pathologist. The correlation between MRI and histological findings was analyzed in terms of depth of invasion. Results. Seventy-nine cases were entered into the study and 75 were evaluable. Accuracy of T2 MR images for invasive and noninvasive disease by Radiologist 1 and Radiologist 2 was 0.8533 and 0.7733, respectively. Accuracy was greater (0.9867 and 0.9467, respectively) for the detection of noninvasive plus microinvasive lesions >5 mm vs invasive lesions ≤5 mm. Dynamic technique provided only limited additional value in the detection of microinvasive cervical carcinoma. Conclusion. Simple T2 MRI is useful in differentiating noninvasive or microinvasive cervical lesions from invasive cervical carcinoma of the cervix >5 mm. (C) 2000 Academic Press.
AB - Objective. We attempted to prospectively determine the role of magnetic resonance imaging (MRI) in very early cervical cancer. Study design. T2-weighted and T1-dynamic enhanced images from patients with invasive or noninvasive lesions of the cervix were reviewed by two radiologists who had no clinical information on these patients. At least 12 longitudinal sections prepared from the surgically removed cervix were reviewed by a pathologist. The correlation between MRI and histological findings was analyzed in terms of depth of invasion. Results. Seventy-nine cases were entered into the study and 75 were evaluable. Accuracy of T2 MR images for invasive and noninvasive disease by Radiologist 1 and Radiologist 2 was 0.8533 and 0.7733, respectively. Accuracy was greater (0.9867 and 0.9467, respectively) for the detection of noninvasive plus microinvasive lesions >5 mm vs invasive lesions ≤5 mm. Dynamic technique provided only limited additional value in the detection of microinvasive cervical carcinoma. Conclusion. Simple T2 MRI is useful in differentiating noninvasive or microinvasive cervical lesions from invasive cervical carcinoma of the cervix >5 mm. (C) 2000 Academic Press.
KW - Cervical carcinoma
KW - Dynamic enhancement
KW - Early stage
KW - Magnetic resonance imaging
UR - http://www.scopus.com/inward/record.url?scp=0033674503&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033674503&partnerID=8YFLogxK
U2 - 10.1006/gyno.2000.5967
DO - 10.1006/gyno.2000.5967
M3 - Article
C2 - 11104618
AN - SCOPUS:0033674503
VL - 79
SP - 451
EP - 456
JO - Gynecologic Oncology
JF - Gynecologic Oncology
SN - 0090-8258
IS - 3
ER -