Negative MRI findings with invasive cervical biopsy may indicate stage IA cervical carcinoma

Keiichi Fujiwara, Eisaku Yoden, Toru Asakawa, Michio Shimizu, Mitsuyoshi Hirokawa, Yoshiki Mikami, Takashi Oda, Ikuo Joja, Yoshinari Imajo, Ichiro Kohno

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Objective. We attempted to prospectively determine the role of magnetic resonance imaging (MRI) in very early cervical cancer. Study design. T2-weighted and T1-dynamic enhanced images from patients with invasive or noninvasive lesions of the cervix were reviewed by two radiologists who had no clinical information on these patients. At least 12 longitudinal sections prepared from the surgically removed cervix were reviewed by a pathologist. The correlation between MRI and histological findings was analyzed in terms of depth of invasion. Results. Seventy-nine cases were entered into the study and 75 were evaluable. Accuracy of T2 MR images for invasive and noninvasive disease by Radiologist 1 and Radiologist 2 was 0.8533 and 0.7733, respectively. Accuracy was greater (0.9867 and 0.9467, respectively) for the detection of noninvasive plus microinvasive lesions >5 mm vs invasive lesions ≤5 mm. Dynamic technique provided only limited additional value in the detection of microinvasive cervical carcinoma. Conclusion. Simple T2 MRI is useful in differentiating noninvasive or microinvasive cervical lesions from invasive cervical carcinoma of the cervix >5 mm. (C) 2000 Academic Press.

Original languageEnglish
Pages (from-to)451-456
Number of pages6
JournalGynecologic Oncology
Volume79
Issue number3
DOIs
Publication statusPublished - 2000

Fingerprint

Cervix Uteri
Magnetic Resonance Imaging
Carcinoma
Biopsy
Uterine Cervical Neoplasms
Radiologists
Pathologists

Keywords

  • Cervical carcinoma
  • Dynamic enhancement
  • Early stage
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology

Cite this

Fujiwara, K., Yoden, E., Asakawa, T., Shimizu, M., Hirokawa, M., Mikami, Y., ... Kohno, I. (2000). Negative MRI findings with invasive cervical biopsy may indicate stage IA cervical carcinoma. Gynecologic Oncology, 79(3), 451-456. https://doi.org/10.1006/gyno.2000.5967

Negative MRI findings with invasive cervical biopsy may indicate stage IA cervical carcinoma. / Fujiwara, Keiichi; Yoden, Eisaku; Asakawa, Toru; Shimizu, Michio; Hirokawa, Mitsuyoshi; Mikami, Yoshiki; Oda, Takashi; Joja, Ikuo; Imajo, Yoshinari; Kohno, Ichiro.

In: Gynecologic Oncology, Vol. 79, No. 3, 2000, p. 451-456.

Research output: Contribution to journalArticle

Fujiwara, K, Yoden, E, Asakawa, T, Shimizu, M, Hirokawa, M, Mikami, Y, Oda, T, Joja, I, Imajo, Y & Kohno, I 2000, 'Negative MRI findings with invasive cervical biopsy may indicate stage IA cervical carcinoma', Gynecologic Oncology, vol. 79, no. 3, pp. 451-456. https://doi.org/10.1006/gyno.2000.5967
Fujiwara, Keiichi ; Yoden, Eisaku ; Asakawa, Toru ; Shimizu, Michio ; Hirokawa, Mitsuyoshi ; Mikami, Yoshiki ; Oda, Takashi ; Joja, Ikuo ; Imajo, Yoshinari ; Kohno, Ichiro. / Negative MRI findings with invasive cervical biopsy may indicate stage IA cervical carcinoma. In: Gynecologic Oncology. 2000 ; Vol. 79, No. 3. pp. 451-456.
@article{06477e41a7a249bb9fa7564ce7790afc,
title = "Negative MRI findings with invasive cervical biopsy may indicate stage IA cervical carcinoma",
abstract = "Objective. We attempted to prospectively determine the role of magnetic resonance imaging (MRI) in very early cervical cancer. Study design. T2-weighted and T1-dynamic enhanced images from patients with invasive or noninvasive lesions of the cervix were reviewed by two radiologists who had no clinical information on these patients. At least 12 longitudinal sections prepared from the surgically removed cervix were reviewed by a pathologist. The correlation between MRI and histological findings was analyzed in terms of depth of invasion. Results. Seventy-nine cases were entered into the study and 75 were evaluable. Accuracy of T2 MR images for invasive and noninvasive disease by Radiologist 1 and Radiologist 2 was 0.8533 and 0.7733, respectively. Accuracy was greater (0.9867 and 0.9467, respectively) for the detection of noninvasive plus microinvasive lesions >5 mm vs invasive lesions ≤5 mm. Dynamic technique provided only limited additional value in the detection of microinvasive cervical carcinoma. Conclusion. Simple T2 MRI is useful in differentiating noninvasive or microinvasive cervical lesions from invasive cervical carcinoma of the cervix >5 mm. (C) 2000 Academic Press.",
keywords = "Cervical carcinoma, Dynamic enhancement, Early stage, Magnetic resonance imaging",
author = "Keiichi Fujiwara and Eisaku Yoden and Toru Asakawa and Michio Shimizu and Mitsuyoshi Hirokawa and Yoshiki Mikami and Takashi Oda and Ikuo Joja and Yoshinari Imajo and Ichiro Kohno",
year = "2000",
doi = "10.1006/gyno.2000.5967",
language = "English",
volume = "79",
pages = "451--456",
journal = "Gynecologic Oncology",
issn = "0090-8258",
publisher = "Academic Press Inc.",
number = "3",

}

TY - JOUR

T1 - Negative MRI findings with invasive cervical biopsy may indicate stage IA cervical carcinoma

AU - Fujiwara, Keiichi

AU - Yoden, Eisaku

AU - Asakawa, Toru

AU - Shimizu, Michio

AU - Hirokawa, Mitsuyoshi

AU - Mikami, Yoshiki

AU - Oda, Takashi

AU - Joja, Ikuo

AU - Imajo, Yoshinari

AU - Kohno, Ichiro

PY - 2000

Y1 - 2000

N2 - Objective. We attempted to prospectively determine the role of magnetic resonance imaging (MRI) in very early cervical cancer. Study design. T2-weighted and T1-dynamic enhanced images from patients with invasive or noninvasive lesions of the cervix were reviewed by two radiologists who had no clinical information on these patients. At least 12 longitudinal sections prepared from the surgically removed cervix were reviewed by a pathologist. The correlation between MRI and histological findings was analyzed in terms of depth of invasion. Results. Seventy-nine cases were entered into the study and 75 were evaluable. Accuracy of T2 MR images for invasive and noninvasive disease by Radiologist 1 and Radiologist 2 was 0.8533 and 0.7733, respectively. Accuracy was greater (0.9867 and 0.9467, respectively) for the detection of noninvasive plus microinvasive lesions >5 mm vs invasive lesions ≤5 mm. Dynamic technique provided only limited additional value in the detection of microinvasive cervical carcinoma. Conclusion. Simple T2 MRI is useful in differentiating noninvasive or microinvasive cervical lesions from invasive cervical carcinoma of the cervix >5 mm. (C) 2000 Academic Press.

AB - Objective. We attempted to prospectively determine the role of magnetic resonance imaging (MRI) in very early cervical cancer. Study design. T2-weighted and T1-dynamic enhanced images from patients with invasive or noninvasive lesions of the cervix were reviewed by two radiologists who had no clinical information on these patients. At least 12 longitudinal sections prepared from the surgically removed cervix were reviewed by a pathologist. The correlation between MRI and histological findings was analyzed in terms of depth of invasion. Results. Seventy-nine cases were entered into the study and 75 were evaluable. Accuracy of T2 MR images for invasive and noninvasive disease by Radiologist 1 and Radiologist 2 was 0.8533 and 0.7733, respectively. Accuracy was greater (0.9867 and 0.9467, respectively) for the detection of noninvasive plus microinvasive lesions >5 mm vs invasive lesions ≤5 mm. Dynamic technique provided only limited additional value in the detection of microinvasive cervical carcinoma. Conclusion. Simple T2 MRI is useful in differentiating noninvasive or microinvasive cervical lesions from invasive cervical carcinoma of the cervix >5 mm. (C) 2000 Academic Press.

KW - Cervical carcinoma

KW - Dynamic enhancement

KW - Early stage

KW - Magnetic resonance imaging

UR - http://www.scopus.com/inward/record.url?scp=0033674503&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033674503&partnerID=8YFLogxK

U2 - 10.1006/gyno.2000.5967

DO - 10.1006/gyno.2000.5967

M3 - Article

C2 - 11104618

AN - SCOPUS:0033674503

VL - 79

SP - 451

EP - 456

JO - Gynecologic Oncology

JF - Gynecologic Oncology

SN - 0090-8258

IS - 3

ER -