Necrotizing soft tissue infection caused by Serratia marcescens: A case report and literature review

Hideharu Hagiya; Masahiro Ojima; Takeshi Yoshida; Takahiro Matsui; Eiichi Morii; Kazuaki Sato; Shinichiro Tahara; Hisao Yoshida; Kazunori Tomono

doi:10.1016/j.jiac.2015.11.013

Necrotizing soft tissue infection caused by Serratia marcescens: A case report and literature review

Hideharu Hagiya, Masahiro Ojima, Takeshi Yoshida, Takahiro Matsui, Eiichi Morii, Kazuaki Sato, Shinichiro Tahara, Hisao Yoshida, Kazunori Tomono

Research output: Contribution to journal › Article

2 Citations (Scopus)

Abstract

A 64-year-old man with advanced liver cirrhosis was transferred to an emergency center due to septic shock and markedly inflamed left leg. Under a clinical diagnosis of necrotizing soft tissue infection (NSTI), the patient undertook intensive therapy but died 25 h after arrival. The pathogenic organism, Serratia marcescens, was later isolated from blood and soft tissue cultures. NSTI is very rarely associated with S. marcescens. A literature review showed that only 16 such cases, including our case, have been reported to date. Our case is the first evidence of an S. marcescens NSTI in a patient with liver cirrhosis. S. marcescens NSTI has an extremely high mortality rate; total mortality and mortality in cases involving the extremities were 75% (12 of 16 cases) and 83.3% (10 of 12 cases), respectively. Physicians need to be aware that S. marcescens can induce fatal infections in community patients.

Original language	English
Pages (from-to)	335-338
Number of pages	4
Journal	Journal of Infection and Chemotherapy
Volume	22
Issue number	5
DOIs	https://doi.org/10.1016/j.jiac.2015.11.013
Publication status	Published - May 1 2016
Externally published	Yes

Keywords

Necrotizing fasciitis
Necrotizing soft tissue infection
Sepsis
Serratia marcescens

ASJC Scopus subject areas

Microbiology (medical)
Pharmacology (medical)
Infectious Diseases

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Hagiya, H., Ojima, M., Yoshida, T., Matsui, T., Morii, E., Sato, K., Tahara, S., Yoshida, H., & Tomono, K. (2016). Necrotizing soft tissue infection caused by Serratia marcescens: A case report and literature review. Journal of Infection and Chemotherapy, 22(5), 335-338. https://doi.org/10.1016/j.jiac.2015.11.013

Necrotizing soft tissue infection caused by Serratia marcescens : A case report and literature review. / Hagiya, Hideharu; Ojima, Masahiro; Yoshida, Takeshi; Matsui, Takahiro; Morii, Eiichi; Sato, Kazuaki; Tahara, Shinichiro; Yoshida, Hisao; Tomono, Kazunori.

In: Journal of Infection and Chemotherapy, Vol. 22, No. 5, 01.05.2016, p. 335-338.

Research output: Contribution to journal › Article

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