Abstract
A 64-year-old man with advanced liver cirrhosis was transferred to an emergency center due to septic shock and markedly inflamed left leg. Under a clinical diagnosis of necrotizing soft tissue infection (NSTI), the patient undertook intensive therapy but died 25 h after arrival. The pathogenic organism, Serratia marcescens, was later isolated from blood and soft tissue cultures. NSTI is very rarely associated with S. marcescens. A literature review showed that only 16 such cases, including our case, have been reported to date. Our case is the first evidence of an S. marcescens NSTI in a patient with liver cirrhosis. S. marcescens NSTI has an extremely high mortality rate; total mortality and mortality in cases involving the extremities were 75% (12 of 16 cases) and 83.3% (10 of 12 cases), respectively. Physicians need to be aware that S. marcescens can induce fatal infections in community patients.
| Original language | English |
|---|---|
| Pages (from-to) | 335-338 |
| Number of pages | 4 |
| Journal | Journal of Infection and Chemotherapy |
| Volume | 22 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 1 2016 |
| Externally published | Yes |
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Keywords
- Necrotizing fasciitis
- Necrotizing soft tissue infection
- Sepsis
- Serratia marcescens
ASJC Scopus subject areas
- Microbiology (medical)
- Pharmacology (medical)
- Infectious Diseases
Cite this
Necrotizing soft tissue infection caused by Serratia marcescens : A case report and literature review. / Hagiya, Hideharu; Ojima, Masahiro; Yoshida, Takeshi; Matsui, Takahiro; Morii, Eiichi; Sato, Kazuaki; Tahara, Shinichiro; Yoshida, Hisao; Tomono, Kazunori.
In: Journal of Infection and Chemotherapy, Vol. 22, No. 5, 01.05.2016, p. 335-338.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Necrotizing soft tissue infection caused by Serratia marcescens
T2 - A case report and literature review
AU - Hagiya, Hideharu
AU - Ojima, Masahiro
AU - Yoshida, Takeshi
AU - Matsui, Takahiro
AU - Morii, Eiichi
AU - Sato, Kazuaki
AU - Tahara, Shinichiro
AU - Yoshida, Hisao
AU - Tomono, Kazunori
PY - 2016/5/1
Y1 - 2016/5/1
N2 - A 64-year-old man with advanced liver cirrhosis was transferred to an emergency center due to septic shock and markedly inflamed left leg. Under a clinical diagnosis of necrotizing soft tissue infection (NSTI), the patient undertook intensive therapy but died 25 h after arrival. The pathogenic organism, Serratia marcescens, was later isolated from blood and soft tissue cultures. NSTI is very rarely associated with S. marcescens. A literature review showed that only 16 such cases, including our case, have been reported to date. Our case is the first evidence of an S. marcescens NSTI in a patient with liver cirrhosis. S. marcescens NSTI has an extremely high mortality rate; total mortality and mortality in cases involving the extremities were 75% (12 of 16 cases) and 83.3% (10 of 12 cases), respectively. Physicians need to be aware that S. marcescens can induce fatal infections in community patients.
AB - A 64-year-old man with advanced liver cirrhosis was transferred to an emergency center due to septic shock and markedly inflamed left leg. Under a clinical diagnosis of necrotizing soft tissue infection (NSTI), the patient undertook intensive therapy but died 25 h after arrival. The pathogenic organism, Serratia marcescens, was later isolated from blood and soft tissue cultures. NSTI is very rarely associated with S. marcescens. A literature review showed that only 16 such cases, including our case, have been reported to date. Our case is the first evidence of an S. marcescens NSTI in a patient with liver cirrhosis. S. marcescens NSTI has an extremely high mortality rate; total mortality and mortality in cases involving the extremities were 75% (12 of 16 cases) and 83.3% (10 of 12 cases), respectively. Physicians need to be aware that S. marcescens can induce fatal infections in community patients.
KW - Necrotizing fasciitis
KW - Necrotizing soft tissue infection
KW - Sepsis
KW - Serratia marcescens
UR - http://www.scopus.com/inward/record.url?scp=84954287528&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84954287528&partnerID=8YFLogxK
U2 - 10.1016/j.jiac.2015.11.013
DO - 10.1016/j.jiac.2015.11.013
M3 - Article
C2 - 26778253
AN - SCOPUS:84954287528
VL - 22
SP - 335
EP - 338
JO - Journal of Infection and Chemotherapy
JF - Journal of Infection and Chemotherapy
SN - 1341-321X
IS - 5
ER -