Necrotizing soft tissue infection caused by Serratia marcescens: A case report and literature review

Hideharu Hagiya, Masahiro Ojima, Takeshi Yoshida, Takahiro Matsui, Eiichi Morii, Kazuaki Sato, Shinichiro Tahara, Hisao Yoshida, Kazunori Tomono

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 64-year-old man with advanced liver cirrhosis was transferred to an emergency center due to septic shock and markedly inflamed left leg. Under a clinical diagnosis of necrotizing soft tissue infection (NSTI), the patient undertook intensive therapy but died 25 h after arrival. The pathogenic organism, Serratia marcescens, was later isolated from blood and soft tissue cultures. NSTI is very rarely associated with S. marcescens. A literature review showed that only 16 such cases, including our case, have been reported to date. Our case is the first evidence of an S. marcescens NSTI in a patient with liver cirrhosis. S. marcescens NSTI has an extremely high mortality rate; total mortality and mortality in cases involving the extremities were 75% (12 of 16 cases) and 83.3% (10 of 12 cases), respectively. Physicians need to be aware that S. marcescens can induce fatal infections in community patients.

Original languageEnglish
Pages (from-to)335-338
Number of pages4
JournalJournal of Infection and Chemotherapy
Volume22
Issue number5
DOIs
Publication statusPublished - May 1 2016
Externally publishedYes

Fingerprint

Serratia marcescens
Soft Tissue Infections
Liver Cirrhosis
Mortality
Septic Shock
Leg
Emergencies
Extremities
Physicians
Infection

Keywords

  • Necrotizing fasciitis
  • Necrotizing soft tissue infection
  • Sepsis
  • Serratia marcescens

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Necrotizing soft tissue infection caused by Serratia marcescens : A case report and literature review. / Hagiya, Hideharu; Ojima, Masahiro; Yoshida, Takeshi; Matsui, Takahiro; Morii, Eiichi; Sato, Kazuaki; Tahara, Shinichiro; Yoshida, Hisao; Tomono, Kazunori.

In: Journal of Infection and Chemotherapy, Vol. 22, No. 5, 01.05.2016, p. 335-338.

Research output: Contribution to journalArticle

Hagiya, H, Ojima, M, Yoshida, T, Matsui, T, Morii, E, Sato, K, Tahara, S, Yoshida, H & Tomono, K 2016, 'Necrotizing soft tissue infection caused by Serratia marcescens: A case report and literature review', Journal of Infection and Chemotherapy, vol. 22, no. 5, pp. 335-338. https://doi.org/10.1016/j.jiac.2015.11.013
Hagiya, Hideharu ; Ojima, Masahiro ; Yoshida, Takeshi ; Matsui, Takahiro ; Morii, Eiichi ; Sato, Kazuaki ; Tahara, Shinichiro ; Yoshida, Hisao ; Tomono, Kazunori. / Necrotizing soft tissue infection caused by Serratia marcescens : A case report and literature review. In: Journal of Infection and Chemotherapy. 2016 ; Vol. 22, No. 5. pp. 335-338.
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