Nazarov cyclization of an indolyl vinyl ketone promoted by acetyl chloride and sodium iodide: Formal synthesis of Bruceolline e

Takumi Abe

doi:10.3987/COM-18-13866

Nazarov cyclization of an indolyl vinyl ketone promoted by acetyl chloride and sodium iodide: Formal synthesis of Bruceolline e

Takumi Abe

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

An acetyl chloride/NaI-mediated Nazarov-type cyclization of an indolyl vinyl ketone was developed to give a cyclopenta[b]indole in high yield. An acyl Finkelstein reaction is a key feature for this unprecedented Nazarov-type cyclization.

Original language	English
Pages (from-to)	490-500
Number of pages	11
Journal	Heterocycles
Volume	96
Issue number	3
DOIs	https://doi.org/10.3987/COM-18-13866
Publication status	Published - 2018
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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title = "Nazarov cyclization of an indolyl vinyl ketone promoted by acetyl chloride and sodium iodide: Formal synthesis of Bruceolline e",

abstract = "An acetyl chloride/NaI-mediated Nazarov-type cyclization of an indolyl vinyl ketone was developed to give a cyclopenta[b]indole in high yield. An acyl Finkelstein reaction is a key feature for this unprecedented Nazarov-type cyclization.",

author = "Takumi Abe",

note = "Funding Information: This work was financially supported by JSPS (KAKENHI Grant Number 16K18849 for T.A.) as a Publisher Copyright: {\textcopyright} 2018 The Japan Institute of Heterocyclic Chemistry.",

year = "2018",

doi = "10.3987/COM-18-13866",

language = "English",

volume = "96",

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journal = "Heterocycles",

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T2 - Formal synthesis of Bruceolline e

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AB - An acetyl chloride/NaI-mediated Nazarov-type cyclization of an indolyl vinyl ketone was developed to give a cyclopenta[b]indole in high yield. An acyl Finkelstein reaction is a key feature for this unprecedented Nazarov-type cyclization.

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M3 - Article

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JF - Heterocycles

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ER -

Nazarov cyclization of an indolyl vinyl ketone promoted by acetyl chloride and sodium iodide: Formal synthesis of Bruceolline e

Abstract

ASJC Scopus subject areas

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