Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2012

General view of the pathogens’ antibacterial susceptibility

Katsunori Yanagihara, Akira Watanabe, Nobuki Aoki, Tetsuya Matsumoto, Masaki Yoshida, Junko Sato, Tomotaro Wakamura, Keisuke Sunakawa, Junichi Kadota, Hiroshi Kiyota, Satoshi Iwata, Mitsuo Kaku, Hideaki Hanaki, Yoshinobu Ohsaki, Satoru Fujiuchi, Manabu Takahashi, Kenichi Takeuchi, Hiroaki Takeda, Hideki Ikeda, Makoto Miki & 69 others Susumu Nakanowatari, Hiroshi Takahashi, Mutsuko Utagawa, Hajime Nishiya, Sayoko Kawakami, Eriko Morino, Jin Takasaki, Kazuhisa Mezaki, Naohiko Chonabayashi, Chie Tanaka, Hideko Sugiura, Hajime Goto, Takeshi Saraya, Daisuke Kurai, Yasuhiro Katono, Rika Inose, Yoshihito Niki, Takahiro Takuma, Makoto Kudo, Shigeru Ehara, Yoshimi Sato, Hiroki Tsukada, Nobuei Watabe, Yasuo Honma, Hiroshige Mikamo, Yuka Yamagishi, Atsushi Nakamura, Minoru Ohashi, Masafumi Seki, Shigeto Hamaguchi, Masahiro Toyokawa, Yasunori Fujikawa, Noriko Mitsuno, Akira Ukimura, Takayuki Miyara, Takahito Nakamura, Keiichi Mikasa, Kei Kasahara, Koji Ui, Saori Fukuda, Akihiro Nakamura, Mika Morimura, Mikio Yamashita, Yoshio Takesue, Yasunao Wada, Keisuke Sugimoto, Nobuchika Kusano, Motoko Nose, Eiichirou Mihara, Masao Kuwabara, Masao Doi, Yaeko Watanabe, Hirokazu Tokuyasu, Satoshi Hino, Kiyoshi Negayama, Hiroshi Mukae, Toshinori Kawanami, Toshiyuki Ota, Masaki Fujita, Junichi Honda, Kazufumi Hiramatsu, Yosuke Aoki, Mami Fukuoka, Hiroki Magarifuchi, Zenzo Nagasawa, Norihito Kaku, Jiro Fujita, Futoshi Higa, Masao Tateyama

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The nationwide surveillance on antimicrobial susceptibility of bacterial respiratory pathogens from the patients in Japan was conducted by Japanese Society of Chemotherapy, Japanese association for infectious diseases and Japanese society for Clinical Microbiology in 2012. The isolates were collected from clinical specimens obtained from well-diagnosed adult patients with respiratory tract infections during the period between January and December in 2012 by three societies. Antimicrobial susceptibility testing was conducted at the central reference laboratory according to the method recommended by Clinical Laboratory Standard Institutes. Susceptibility testing was evaluated in 1236 strains (232 Staphylococcus aureus, 225 Streptococcus pneumoniae, 16 Streptococcus pyogenes, 231 Haemophilus influenzae, 147 Moraxella catarrhalis, 167 Klebsiella pneumoniae and 218 Pseudomonas aeruginosa). Ratio of methicillin-resistant S. aureus was 51.3%, and those of penicillin-intermediate S. pneumoniae was 0.4%. Among H. influenzae, 5.6% of them were found to be β-lactamase-producing ampicillin-resistant strains, and 37.2% to be β-lactamase-non-producing ampicillin-resistant strains. Extended spectrum β-lactamase-producing K. pneumoniae and multi-drug resistant P. aeruginosa with metallo β-lactamase were 4.2% and 3.2%, respectively. Continuous national surveillance is important to determine the actual situation of the resistance shown by bacterial respiratory pathogens to antimicrobial agents.

Original languageEnglish
Pages (from-to)587-597
Number of pages11
JournalJournal of Infection and Chemotherapy
Volume23
Issue number9
DOIs
Publication statusPublished - Sep 1 2017

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Haemophilus influenzae
Klebsiella pneumoniae
Ampicillin
Streptococcus pneumoniae
Microbiology
Pseudomonas aeruginosa
Communicable Diseases
Moraxella (Branhamella) catarrhalis
Drug Therapy
Streptococcus pyogenes
Methicillin-Resistant Staphylococcus aureus
Anti-Infective Agents
Respiratory Tract Infections
Penicillins
Staphylococcus aureus
Japan
Pharmaceutical Preparations

Keywords

  • Resistance
  • Respiratory tract infection
  • Surveillance
  • Susceptibility

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2012 : General view of the pathogens’ antibacterial susceptibility. / Yanagihara, Katsunori; Watanabe, Akira; Aoki, Nobuki; Matsumoto, Tetsuya; Yoshida, Masaki; Sato, Junko; Wakamura, Tomotaro; Sunakawa, Keisuke; Kadota, Junichi; Kiyota, Hiroshi; Iwata, Satoshi; Kaku, Mitsuo; Hanaki, Hideaki; Ohsaki, Yoshinobu; Fujiuchi, Satoru; Takahashi, Manabu; Takeuchi, Kenichi; Takeda, Hiroaki; Ikeda, Hideki; Miki, Makoto; Nakanowatari, Susumu; Takahashi, Hiroshi; Utagawa, Mutsuko; Nishiya, Hajime; Kawakami, Sayoko; Morino, Eriko; Takasaki, Jin; Mezaki, Kazuhisa; Chonabayashi, Naohiko; Tanaka, Chie; Sugiura, Hideko; Goto, Hajime; Saraya, Takeshi; Kurai, Daisuke; Katono, Yasuhiro; Inose, Rika; Niki, Yoshihito; Takuma, Takahiro; Kudo, Makoto; Ehara, Shigeru; Sato, Yoshimi; Tsukada, Hiroki; Watabe, Nobuei; Honma, Yasuo; Mikamo, Hiroshige; Yamagishi, Yuka; Nakamura, Atsushi; Ohashi, Minoru; Seki, Masafumi; Hamaguchi, Shigeto; Toyokawa, Masahiro; Fujikawa, Yasunori; Mitsuno, Noriko; Ukimura, Akira; Miyara, Takayuki; Nakamura, Takahito; Mikasa, Keiichi; Kasahara, Kei; Ui, Koji; Fukuda, Saori; Nakamura, Akihiro; Morimura, Mika; Yamashita, Mikio; Takesue, Yoshio; Wada, Yasunao; Sugimoto, Keisuke; Kusano, Nobuchika; Nose, Motoko; Mihara, Eiichirou; Kuwabara, Masao; Doi, Masao; Watanabe, Yaeko; Tokuyasu, Hirokazu; Hino, Satoshi; Negayama, Kiyoshi; Mukae, Hiroshi; Kawanami, Toshinori; Ota, Toshiyuki; Fujita, Masaki; Honda, Junichi; Hiramatsu, Kazufumi; Aoki, Yosuke; Fukuoka, Mami; Magarifuchi, Hiroki; Nagasawa, Zenzo; Kaku, Norihito; Fujita, Jiro; Higa, Futoshi; Tateyama, Masao.

In: Journal of Infection and Chemotherapy, Vol. 23, No. 9, 01.09.2017, p. 587-597.

Research output: Contribution to journalArticle

Yanagihara, K, Watanabe, A, Aoki, N, Matsumoto, T, Yoshida, M, Sato, J, Wakamura, T, Sunakawa, K, Kadota, J, Kiyota, H, Iwata, S, Kaku, M, Hanaki, H, Ohsaki, Y, Fujiuchi, S, Takahashi, M, Takeuchi, K, Takeda, H, Ikeda, H, Miki, M, Nakanowatari, S, Takahashi, H, Utagawa, M, Nishiya, H, Kawakami, S, Morino, E, Takasaki, J, Mezaki, K, Chonabayashi, N, Tanaka, C, Sugiura, H, Goto, H, Saraya, T, Kurai, D, Katono, Y, Inose, R, Niki, Y, Takuma, T, Kudo, M, Ehara, S, Sato, Y, Tsukada, H, Watabe, N, Honma, Y, Mikamo, H, Yamagishi, Y, Nakamura, A, Ohashi, M, Seki, M, Hamaguchi, S, Toyokawa, M, Fujikawa, Y, Mitsuno, N, Ukimura, A, Miyara, T, Nakamura, T, Mikasa, K, Kasahara, K, Ui, K, Fukuda, S, Nakamura, A, Morimura, M, Yamashita, M, Takesue, Y, Wada, Y, Sugimoto, K, Kusano, N, Nose, M, Mihara, E, Kuwabara, M, Doi, M, Watanabe, Y, Tokuyasu, H, Hino, S, Negayama, K, Mukae, H, Kawanami, T, Ota, T, Fujita, M, Honda, J, Hiramatsu, K, Aoki, Y, Fukuoka, M, Magarifuchi, H, Nagasawa, Z, Kaku, N, Fujita, J, Higa, F & Tateyama, M 2017, 'Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2012: General view of the pathogens’ antibacterial susceptibility', Journal of Infection and Chemotherapy, vol. 23, no. 9, pp. 587-597. https://doi.org/10.1016/j.jiac.2017.05.010
Yanagihara, Katsunori ; Watanabe, Akira ; Aoki, Nobuki ; Matsumoto, Tetsuya ; Yoshida, Masaki ; Sato, Junko ; Wakamura, Tomotaro ; Sunakawa, Keisuke ; Kadota, Junichi ; Kiyota, Hiroshi ; Iwata, Satoshi ; Kaku, Mitsuo ; Hanaki, Hideaki ; Ohsaki, Yoshinobu ; Fujiuchi, Satoru ; Takahashi, Manabu ; Takeuchi, Kenichi ; Takeda, Hiroaki ; Ikeda, Hideki ; Miki, Makoto ; Nakanowatari, Susumu ; Takahashi, Hiroshi ; Utagawa, Mutsuko ; Nishiya, Hajime ; Kawakami, Sayoko ; Morino, Eriko ; Takasaki, Jin ; Mezaki, Kazuhisa ; Chonabayashi, Naohiko ; Tanaka, Chie ; Sugiura, Hideko ; Goto, Hajime ; Saraya, Takeshi ; Kurai, Daisuke ; Katono, Yasuhiro ; Inose, Rika ; Niki, Yoshihito ; Takuma, Takahiro ; Kudo, Makoto ; Ehara, Shigeru ; Sato, Yoshimi ; Tsukada, Hiroki ; Watabe, Nobuei ; Honma, Yasuo ; Mikamo, Hiroshige ; Yamagishi, Yuka ; Nakamura, Atsushi ; Ohashi, Minoru ; Seki, Masafumi ; Hamaguchi, Shigeto ; Toyokawa, Masahiro ; Fujikawa, Yasunori ; Mitsuno, Noriko ; Ukimura, Akira ; Miyara, Takayuki ; Nakamura, Takahito ; Mikasa, Keiichi ; Kasahara, Kei ; Ui, Koji ; Fukuda, Saori ; Nakamura, Akihiro ; Morimura, Mika ; Yamashita, Mikio ; Takesue, Yoshio ; Wada, Yasunao ; Sugimoto, Keisuke ; Kusano, Nobuchika ; Nose, Motoko ; Mihara, Eiichirou ; Kuwabara, Masao ; Doi, Masao ; Watanabe, Yaeko ; Tokuyasu, Hirokazu ; Hino, Satoshi ; Negayama, Kiyoshi ; Mukae, Hiroshi ; Kawanami, Toshinori ; Ota, Toshiyuki ; Fujita, Masaki ; Honda, Junichi ; Hiramatsu, Kazufumi ; Aoki, Yosuke ; Fukuoka, Mami ; Magarifuchi, Hiroki ; Nagasawa, Zenzo ; Kaku, Norihito ; Fujita, Jiro ; Higa, Futoshi ; Tateyama, Masao. / Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2012 : General view of the pathogens’ antibacterial susceptibility. In: Journal of Infection and Chemotherapy. 2017 ; Vol. 23, No. 9. pp. 587-597.
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AU - Yanagihara, Katsunori

AU - Watanabe, Akira

AU - Aoki, Nobuki

AU - Matsumoto, Tetsuya

AU - Yoshida, Masaki

AU - Sato, Junko

AU - Wakamura, Tomotaro

AU - Sunakawa, Keisuke

AU - Kadota, Junichi

AU - Kiyota, Hiroshi

AU - Iwata, Satoshi

AU - Kaku, Mitsuo

AU - Hanaki, Hideaki

AU - Ohsaki, Yoshinobu

AU - Fujiuchi, Satoru

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AU - Takeuchi, Kenichi

AU - Takeda, Hiroaki

AU - Ikeda, Hideki

AU - Miki, Makoto

AU - Nakanowatari, Susumu

AU - Takahashi, Hiroshi

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AU - Nishiya, Hajime

AU - Kawakami, Sayoko

AU - Morino, Eriko

AU - Takasaki, Jin

AU - Mezaki, Kazuhisa

AU - Chonabayashi, Naohiko

AU - Tanaka, Chie

AU - Sugiura, Hideko

AU - Goto, Hajime

AU - Saraya, Takeshi

AU - Kurai, Daisuke

AU - Katono, Yasuhiro

AU - Inose, Rika

AU - Niki, Yoshihito

AU - Takuma, Takahiro

AU - Kudo, Makoto

AU - Ehara, Shigeru

AU - Sato, Yoshimi

AU - Tsukada, Hiroki

AU - Watabe, Nobuei

AU - Honma, Yasuo

AU - Mikamo, Hiroshige

AU - Yamagishi, Yuka

AU - Nakamura, Atsushi

AU - Ohashi, Minoru

AU - Seki, Masafumi

AU - Hamaguchi, Shigeto

AU - Toyokawa, Masahiro

AU - Fujikawa, Yasunori

AU - Mitsuno, Noriko

AU - Ukimura, Akira

AU - Miyara, Takayuki

AU - Nakamura, Takahito

AU - Mikasa, Keiichi

AU - Kasahara, Kei

AU - Ui, Koji

AU - Fukuda, Saori

AU - Nakamura, Akihiro

AU - Morimura, Mika

AU - Yamashita, Mikio

AU - Takesue, Yoshio

AU - Wada, Yasunao

AU - Sugimoto, Keisuke

AU - Kusano, Nobuchika

AU - Nose, Motoko

AU - Mihara, Eiichirou

AU - Kuwabara, Masao

AU - Doi, Masao

AU - Watanabe, Yaeko

AU - Tokuyasu, Hirokazu

AU - Hino, Satoshi

AU - Negayama, Kiyoshi

AU - Mukae, Hiroshi

AU - Kawanami, Toshinori

AU - Ota, Toshiyuki

AU - Fujita, Masaki

AU - Honda, Junichi

AU - Hiramatsu, Kazufumi

AU - Aoki, Yosuke

AU - Fukuoka, Mami

AU - Magarifuchi, Hiroki

AU - Nagasawa, Zenzo

AU - Kaku, Norihito

AU - Fujita, Jiro

AU - Higa, Futoshi

AU - Tateyama, Masao

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KW - Resistance

KW - Respiratory tract infection

KW - Surveillance

KW - Susceptibility

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