TY - JOUR
T1 - Narrow band imaging under less-air condition improves the visibility of superficial esophageal squamous cell carcinoma
AU - Iwatsubo, Taro
AU - Ishihara, Ryu
AU - Yamasaki, Yasushi
AU - Tonai, Yusuke
AU - Hamada, Kenta
AU - Kato, Minoru
AU - Suzuki, Sho
AU - Kono, Mitsuhiro
AU - Fukuda, Hiromu
AU - Shimamoto, Yusaku
AU - Nakagawa, Kentaro
AU - Ohmori, Masayasu
AU - Arao, Masamichi
AU - Matsuno, Kenshi
AU - Iwagami, Hiroyoshi
AU - Inoue, Shuntaro
AU - Nakahira, Hiroko
AU - Matsuura, Noriko
AU - Shichijo, Satoki
AU - Maekawa, Akira
AU - Kanesaka, Takashi
AU - Takeuchi, Yoji
AU - Higashino, Koji
AU - Uedo, Noriya
AU - Higuchi, Kazuhide
N1 - Publisher Copyright:
© 2020, The Author(s).
PY - 2020/12
Y1 - 2020/12
N2 - Background: The current virtual chromoendoscopy equipment cannot completely detect superficial squamous cell carcinoma (SCC) in the esophagus, despite its development in the recent years. Thus, in this study, we aimed to elucidate the appropriate air volume during endoscopic observation to improve the visibility of esophageal SCC. Methods: This retrospective study included a total of 101 flat type esophageal SCCs identified between April 2017 and January 2019 at the Department of Gastrointestinal Oncology, Osaka International Cancer Institute. Video images of narrow band imaging (NBI) under both less-air and standard-air conditions were recorded digitally. Videos were evaluated by five endoscopists. Relative visibility between less-air and standard-air conditions of the brownish area, brownish color change of the epithelium, and dilated intrapapillary capillary loop (IPCL) were graded as 5 (definitely better under less-air condition) to 1 (definitely worse under less-air condition), with 3 indicating average visibility (equivalent to standard-air observation). Results: The mean (standard deviation) visibility score of the brownish area, brownish color change of the epithelium, and dilated IPCLs under less-air condition were 3.94 (0.58), 3.73 (0.57), and 4.13 (0.60), respectively, which were significantly better than that under standard-air condition (p < 0.0001). Esophageal SCC evaluated as ≥ 4 in the mean visibility score of the brownish area, brownish color change of the epithelium, and dilated IPCLs accounted for 50% (51/101 lesions), 34% (34/101 lesions), and 67% (68/101 lesions), respectively. Conclusions: The present results suggested that NBI with less air might improve the visibility of flat type esophageal SCC compared with NBI with standard air. Less-air NBI observation may facilitate the detection of flat type esophageal SCC. Trial registration: The present study is a non-intervention trial.
AB - Background: The current virtual chromoendoscopy equipment cannot completely detect superficial squamous cell carcinoma (SCC) in the esophagus, despite its development in the recent years. Thus, in this study, we aimed to elucidate the appropriate air volume during endoscopic observation to improve the visibility of esophageal SCC. Methods: This retrospective study included a total of 101 flat type esophageal SCCs identified between April 2017 and January 2019 at the Department of Gastrointestinal Oncology, Osaka International Cancer Institute. Video images of narrow band imaging (NBI) under both less-air and standard-air conditions were recorded digitally. Videos were evaluated by five endoscopists. Relative visibility between less-air and standard-air conditions of the brownish area, brownish color change of the epithelium, and dilated intrapapillary capillary loop (IPCL) were graded as 5 (definitely better under less-air condition) to 1 (definitely worse under less-air condition), with 3 indicating average visibility (equivalent to standard-air observation). Results: The mean (standard deviation) visibility score of the brownish area, brownish color change of the epithelium, and dilated IPCLs under less-air condition were 3.94 (0.58), 3.73 (0.57), and 4.13 (0.60), respectively, which were significantly better than that under standard-air condition (p < 0.0001). Esophageal SCC evaluated as ≥ 4 in the mean visibility score of the brownish area, brownish color change of the epithelium, and dilated IPCLs accounted for 50% (51/101 lesions), 34% (34/101 lesions), and 67% (68/101 lesions), respectively. Conclusions: The present results suggested that NBI with less air might improve the visibility of flat type esophageal SCC compared with NBI with standard air. Less-air NBI observation may facilitate the detection of flat type esophageal SCC. Trial registration: The present study is a non-intervention trial.
KW - Less air
KW - Narrow band imaging
KW - Superficial esophageal squamous cell carcinoma
UR - http://www.scopus.com/inward/record.url?scp=85096335923&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85096335923&partnerID=8YFLogxK
U2 - 10.1186/s12876-020-01534-2
DO - 10.1186/s12876-020-01534-2
M3 - Article
C2 - 33213383
AN - SCOPUS:85096335923
SN - 1471-230X
VL - 20
JO - BMC Gastroenterology
JF - BMC Gastroenterology
IS - 1
M1 - 389
ER -
