Nakinadines B-F: new pyridine alkaloids with a β-amino acid moiety from sponge Amphimedon sp.

Takami Nishi, Takaaki Kubota, Jane Fromont, Takuma Sasaki, Jun'ichi Kobayashi

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

Five new 3-alkylpyridine alkaloids with a β-amino acid moiety, nakinadines B-F (1-5), have been isolated from an Okinawan marine sponge Amphimedon sp. (SS-1059), and the structures and stereochemistry were elucidated by spectroscopic data. Nakinadines B (1) and C (2) showed modest cytotoxicity.

Original languageEnglish
Pages (from-to)3127-3132
Number of pages6
JournalTetrahedron
Volume64
Issue number14
DOIs
Publication statusPublished - Mar 31 2008
Externally publishedYes

Keywords

  • β-Amino acid
  • Alkaloid
  • Nakinadines B-F
  • Pyridine
  • Sponge

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Nakinadines B-F: new pyridine alkaloids with a β-amino acid moiety from sponge Amphimedon sp.'. Together they form a unique fingerprint.

Cite this