Nakijiquinone S and nakijinol C, new meroterpenoids from a marine sponge of the family spongiidae

Haruna Suzuki, Takaaki Kubota, Azusa Takahashi-Nakaguchi, Jane Fromont, Tohru Gonoi, Junichi Kobayashi

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

New meroterpenoids, nakijiquinone S (1) and nakijinol C (2), have been isolated from an Okinawan marine sponge of the family Spongiidae. The gross structures and relative stereochemistries of 1 and 2 were elucidated on the basis of their spectral data. Nakijiquinone S (1) and nakijinol C (2) were new meroterpenoids consisting of a clerodane-type decalin ring connected to a 2-butoxy-5-hydroxy-benzoquinone unit or methyl 2,3,4-trihydroxybenzoate unit through a methylene, respectively. Nakijiquinone S (1) and nakijinol C (2) showed antimicrobial activities against several bacteria and fungi.

Original languageEnglish
Pages (from-to)209-212
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume62
Issue number2
DOIs
Publication statusPublished - Feb 2014
Externally publishedYes

Keywords

  • Antimicrobial activity
  • Marine sponge
  • Meroterpenoid
  • Nakijinol C
  • Nakijiquinone S
  • Spongiidae

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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