TY - JOUR
T1 - Nakijiquinone S and nakijinol C, new meroterpenoids from a marine sponge of the family spongiidae
AU - Suzuki, Haruna
AU - Kubota, Takaaki
AU - Takahashi-Nakaguchi, Azusa
AU - Fromont, Jane
AU - Gonoi, Tohru
AU - Kobayashi, Junichi
PY - 2014/2
Y1 - 2014/2
N2 - New meroterpenoids, nakijiquinone S (1) and nakijinol C (2), have been isolated from an Okinawan marine sponge of the family Spongiidae. The gross structures and relative stereochemistries of 1 and 2 were elucidated on the basis of their spectral data. Nakijiquinone S (1) and nakijinol C (2) were new meroterpenoids consisting of a clerodane-type decalin ring connected to a 2-butoxy-5-hydroxy-benzoquinone unit or methyl 2,3,4-trihydroxybenzoate unit through a methylene, respectively. Nakijiquinone S (1) and nakijinol C (2) showed antimicrobial activities against several bacteria and fungi.
AB - New meroterpenoids, nakijiquinone S (1) and nakijinol C (2), have been isolated from an Okinawan marine sponge of the family Spongiidae. The gross structures and relative stereochemistries of 1 and 2 were elucidated on the basis of their spectral data. Nakijiquinone S (1) and nakijinol C (2) were new meroterpenoids consisting of a clerodane-type decalin ring connected to a 2-butoxy-5-hydroxy-benzoquinone unit or methyl 2,3,4-trihydroxybenzoate unit through a methylene, respectively. Nakijiquinone S (1) and nakijinol C (2) showed antimicrobial activities against several bacteria and fungi.
KW - Antimicrobial activity
KW - Marine sponge
KW - Meroterpenoid
KW - Nakijinol C
KW - Nakijiquinone S
KW - Spongiidae
UR - http://www.scopus.com/inward/record.url?scp=84894260415&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84894260415&partnerID=8YFLogxK
U2 - 10.1248/cpb.c13-00810
DO - 10.1248/cpb.c13-00810
M3 - Article
C2 - 24492592
AN - SCOPUS:84894260415
SN - 0009-2363
VL - 62
SP - 209
EP - 212
JO - Chemical and Pharmaceutical Bulletin
JF - Chemical and Pharmaceutical Bulletin
IS - 2
ER -
