Abstract
Two new dimeric bromopyrrole alkaloids, nagelamides Q (1) and R (2), have been isolated fromSROkinawan marine sponges of the genus Agelas (SS-1134 and SS-956, respectively), and the structures and stereochemistry were elucidated from spectroscopic data. Nagelamide Q (1) is a rare dimeric bromopyrrole alkaloid possessing a pyrrolidine ring, while nagelamide R (2) is the first bromopyrrole alkaloid having an oxazoline ring. Nagelamides Q (1) and R (2) showed antimicrobial activity.
Original language | English |
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Pages (from-to) | 1785-1788 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 11 |
Issue number | 8 |
DOIs | |
Publication status | Published - Apr 16 2009 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry