Nagelamide J, a novel dimeric bromopyrrole alkaloid from a sponge agelas species

Atsushi Araki; Masashi Tsuda; Takaaki Kubota; Yuzuru Mikami; Jane Fromont; Ju N.ichi Kobayashi

doi:10.1021/ol0707867

Nagelamide J, a novel dimeric bromopyrrole alkaloid from a sponge agelas species

Atsushi Araki, Masashi Tsuda, Takaaki Kubota, Yuzuru Mikami, Jane Fromont, Ju N.ichi Kobayashi

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

A novel dimeric bromopyrrole alkaloid, nagelamide J (1), with antimicrobial activity has been isolated from an Okinawan marine sponge Agelas species, and the structure and stereochemistry were elucidated from spectroscopic data. Nagelamide J (1) is the first bromopyrrole alkaloid possessing a cyclopentane ring fused to an amino imidazole ring.

Original language	English
Pages (from-to)	2369-2371
Number of pages	3
Journal	Organic Letters
Volume	9
Issue number	12
DOIs	https://doi.org/10.1021/ol0707867
Publication status	Published - Jun 7 2007
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/ol0707867

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abstract = "A novel dimeric bromopyrrole alkaloid, nagelamide J (1), with antimicrobial activity has been isolated from an Okinawan marine sponge Agelas species, and the structure and stereochemistry were elucidated from spectroscopic data. Nagelamide J (1) is the first bromopyrrole alkaloid possessing a cyclopentane ring fused to an amino imidazole ring.",

author = "Atsushi Araki and Masashi Tsuda and Takaaki Kubota and Yuzuru Mikami and Jane Fromont and Kobayashi, {Ju N.ichi}",

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AU - Araki, Atsushi

AU - Tsuda, Masashi

AU - Kubota, Takaaki

AU - Mikami, Yuzuru

AU - Fromont, Jane

AU - Kobayashi, Ju N.ichi

PY - 2007/6/7

Y1 - 2007/6/7

N2 - A novel dimeric bromopyrrole alkaloid, nagelamide J (1), with antimicrobial activity has been isolated from an Okinawan marine sponge Agelas species, and the structure and stereochemistry were elucidated from spectroscopic data. Nagelamide J (1) is the first bromopyrrole alkaloid possessing a cyclopentane ring fused to an amino imidazole ring.

AB - A novel dimeric bromopyrrole alkaloid, nagelamide J (1), with antimicrobial activity has been isolated from an Okinawan marine sponge Agelas species, and the structure and stereochemistry were elucidated from spectroscopic data. Nagelamide J (1) is the first bromopyrrole alkaloid possessing a cyclopentane ring fused to an amino imidazole ring.

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Nagelamide J, a novel dimeric bromopyrrole alkaloid from a sponge agelas species

Abstract

ASJC Scopus subject areas

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