Nagelamide I and 2,2'-Didebromonagelamide B, new dimeric bromopyrrole-imidazole alkaloids from a marine sponge agelas sp

Takahiro Iwai; Takaaki Kubota; Jane Fromont; Junichi Kobayashi

doi:10.1248/cpb.c13-00821

Nagelamide I and 2,2'-Didebromonagelamide B, new dimeric bromopyrrole-imidazole alkaloids from a marine sponge agelas sp

Takahiro Iwai, Takaaki Kubota, Jane Fromont, Junichi Kobayashi

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

New dimeric bromopyrrole-imidazole alkaloids, nagelamide I (1) and 2,2-didebromonagelamide B (2), have been isolated from an Okinawan marine sponge Agelas species. The structures of 1 and 2 were elucidated based on analyses of the spectral data. Nagelamide I (1) was the first symmetric dimeric bromopyrrole- imidazole alkaloid consisting of two subunits connected with a single bond.

Original language	English
Pages (from-to)	213-216
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	62
Issue number	2
DOIs	https://doi.org/10.1248/cpb.c13-00821
Publication status	Published - Feb 2014
Externally published	Yes

Keywords

2-2'-didebromonagelamide B
Agelas sp.
Dimeric bromopyrrole-imidazole alkaloid
Marine sponge
Nagelamide I

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1248/cpb.c13-00821

Cite this

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abstract = "New dimeric bromopyrrole-imidazole alkaloids, nagelamide I (1) and 2,2-didebromonagelamide B (2), have been isolated from an Okinawan marine sponge Agelas species. The structures of 1 and 2 were elucidated based on analyses of the spectral data. Nagelamide I (1) was the first symmetric dimeric bromopyrrole- imidazole alkaloid consisting of two subunits connected with a single bond.",

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author = "Takahiro Iwai and Takaaki Kubota and Jane Fromont and Junichi Kobayashi",

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doi = "10.1248/cpb.c13-00821",

language = "English",

volume = "62",

pages = "213--216",

journal = "Chemical and Pharmaceutical Bulletin",

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T1 - Nagelamide I and 2,2'-Didebromonagelamide B, new dimeric bromopyrrole-imidazole alkaloids from a marine sponge agelas sp

AU - Iwai, Takahiro

AU - Kubota, Takaaki

AU - Fromont, Jane

AU - Kobayashi, Junichi

PY - 2014/2

Y1 - 2014/2

N2 - New dimeric bromopyrrole-imidazole alkaloids, nagelamide I (1) and 2,2-didebromonagelamide B (2), have been isolated from an Okinawan marine sponge Agelas species. The structures of 1 and 2 were elucidated based on analyses of the spectral data. Nagelamide I (1) was the first symmetric dimeric bromopyrrole- imidazole alkaloid consisting of two subunits connected with a single bond.

AB - New dimeric bromopyrrole-imidazole alkaloids, nagelamide I (1) and 2,2-didebromonagelamide B (2), have been isolated from an Okinawan marine sponge Agelas species. The structures of 1 and 2 were elucidated based on analyses of the spectral data. Nagelamide I (1) was the first symmetric dimeric bromopyrrole- imidazole alkaloid consisting of two subunits connected with a single bond.

KW - 2-2'-didebromonagelamide B

KW - Agelas sp.

KW - Dimeric bromopyrrole-imidazole alkaloid

KW - Marine sponge

KW - Nagelamide I

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DO - 10.1248/cpb.c13-00821

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VL - 62

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JO - Chemical and Pharmaceutical Bulletin

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Nagelamide I and 2,2'-Didebromonagelamide B, new dimeric bromopyrrole-imidazole alkaloids from a marine sponge agelas sp

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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