Abstract
New dimeric bromopyrrole-imidazole alkaloids, nagelamide I (1) and 2,2-didebromonagelamide B (2), have been isolated from an Okinawan marine sponge Agelas species. The structures of 1 and 2 were elucidated based on analyses of the spectral data. Nagelamide I (1) was the first symmetric dimeric bromopyrrole- imidazole alkaloid consisting of two subunits connected with a single bond.
Original language | English |
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Pages (from-to) | 213-216 |
Number of pages | 4 |
Journal | Chemical and Pharmaceutical Bulletin |
Volume | 62 |
Issue number | 2 |
DOIs | |
Publication status | Published - Feb 2014 |
Externally published | Yes |
Keywords
- 2-2'-didebromonagelamide B
- Agelas sp.
- Dimeric bromopyrrole-imidazole alkaloid
- Marine sponge
- Nagelamide I
ASJC Scopus subject areas
- Chemistry(all)
- Drug Discovery