Abstract
Nomura et al. report the neural mechanisms for NaCl-induced sympathetically activated blood pressure increases. [Na + ] sensing by Na x in the OVLT and subsequent ASIC1a activation in OVLT(→PVN) neurons by H + released from Na x -positive glial cells are primary steps in this process.
Original language | English |
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Pages (from-to) | 60-75.e6 |
Journal | Neuron |
Volume | 101 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 2 2019 |
Externally published | Yes |
Keywords
- ASIC channel
- CSF
- Na channel
- OVLT
- PVN
- blood
- blood pressure
- body fluid
- salt-sensitive hypertension
- sodium concentration
ASJC Scopus subject areas
- Neuroscience(all)