TY - JOUR
T1 - Myxofibrosarcoma
T2 - Clinical and prognostic value of mri features
AU - Spinnato, Paolo
AU - Sambri, Andrea
AU - Fujiwara, Tomohiro
AU - Ceccarelli, Luca
AU - Clinca, Roberta
AU - Medellin, Manuel R.
AU - De Paolis, Massimiliano
AU - Donati, Davide M.
AU - Bianchi, Giuseppe
N1 - Publisher Copyright:
© 2021 Bentham Science Publishers.
PY - 2021
Y1 - 2021
N2 - Myxofibrosarcoma is one of the most common soft tissue sarcomas in the elderly. It is characterized by an extremely high rate of local recurrence, higher than other soft tissue tumors, and a relatively low risk of distant metastases.Magnetic resonance imaging (MRI) is the imaging modality of choice for the assessment of myxofibrosarcoma, which plays a key role in the preoperative setting of these patients. MRI features associated with the high risk of local recurrence are: high myxoid matrix content (water-like appearance of the lesions), high grade of contrast enhancement and presence of an infiltrative pattern (“tail sign”). On the other hand, MRI features associated with worse sarcoma specific survival are: large size of the lesion, deep location, high grade of contrast enhancement. Recognizing the above-mentioned imaging features of myxofibrosarcoma may be helpful in stratifying the risk for local recurrence and disease-specific survival. Moreover, the surgical planning should be adjusted according to the MRI features.
AB - Myxofibrosarcoma is one of the most common soft tissue sarcomas in the elderly. It is characterized by an extremely high rate of local recurrence, higher than other soft tissue tumors, and a relatively low risk of distant metastases.Magnetic resonance imaging (MRI) is the imaging modality of choice for the assessment of myxofibrosarcoma, which plays a key role in the preoperative setting of these patients. MRI features associated with the high risk of local recurrence are: high myxoid matrix content (water-like appearance of the lesions), high grade of contrast enhancement and presence of an infiltrative pattern (“tail sign”). On the other hand, MRI features associated with worse sarcoma specific survival are: large size of the lesion, deep location, high grade of contrast enhancement. Recognizing the above-mentioned imaging features of myxofibrosarcoma may be helpful in stratifying the risk for local recurrence and disease-specific survival. Moreover, the surgical planning should be adjusted according to the MRI features.
KW - Local neoplasm re-currence
KW - Magnetic resonance imaging
KW - Neoplasm invasivenes
KW - Prognosis
KW - Sarcoma
KW - Soft tissue neoplasm
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U2 - 10.2174/1573405616999200729152135
DO - 10.2174/1573405616999200729152135
M3 - Review article
C2 - 32729425
AN - SCOPUS:85102987974
VL - 17
SP - 217
EP - 224
JO - Current Medical Imaging
JF - Current Medical Imaging
SN - 1573-4056
IS - 2
ER -