Mutations in the C1 element of the insulin promoter lead to diabetic phenotypes in homozygous mice

Agriculture & Biology

• insulin 85%
• promoter regions 70%
• mutation 67%
• phenotype 64%
• mice 56%
• gene editing 30%
• in vivo studies 26%
• in vitro studies 23%
• transcription factors 18%
• transcription (genetics) 18%
• cells 15%
• loci 14%
• genes 8%

Medicine & Life Sciences

• Genetic Promoter Regions 70%
• Insulin 66%
• Phenotype 58%
• Mutation 54%
• Technology 31%
• Gene Editing 29%
• Transcription Factors 18%
• In Vitro Techniques 10%
• Genes 9%

Chemical Compounds

• Insulin Derivative 100%
• Mutation 82%