Multitracer study on uptake and excretion of trace elements in rats

Makoto Yanaga, Shuichi Enomoto, Rieko Hirunuma, Riko Furuta, Kazutoyo Endo, Akira Tanaka, Shizuko Ambe, Machiko Tozawa, Fumitoshi Ambe

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The multitracer technique was first applied to the investigation of the uptake and excretion behaviour of trace elements in rats. A multitracer solution, prepared by irradiation of a gold target with a 14N-beam from the RIKEN Ring Cyclotron, was orally administered to male Wistar rats. The uptake and excretion rates of 23 elements, Be, Mn, Co, Zn, As, Rb, Sr, Y, Zr, Ce, Pm, Eu, Gd, Tb, Er, Tm, Yb, Lu, Hf, W, Re, Ir and Pt, were simultaneously determined under strictly identical experimental conditions. For some of the elements, the results obtained were consistent with previous reports on uptake and excretion of the elements in animals. For the other elements, unique behaviour was revealed for the first time as described in the present work. These results show that the multitracer technique has excellent reliability and versatility for a comparative study of the uptake and excretion of many different elements in animals.

Original languageEnglish
Pages (from-to)235-240
Number of pages6
JournalApplied Radiation and Isotopes
Volume47
Issue number2
DOIs
Publication statusPublished - 1996
Externally publishedYes

Fingerprint

excretion
trace elements
rats
animals
versatility
cyclotrons
gold
irradiation
rings

ASJC Scopus subject areas

  • Radiation

Cite this

Yanaga, M., Enomoto, S., Hirunuma, R., Furuta, R., Endo, K., Tanaka, A., ... Ambe, F. (1996). Multitracer study on uptake and excretion of trace elements in rats. Applied Radiation and Isotopes, 47(2), 235-240. https://doi.org/10.1016/0969-8043(95)00279-0

Multitracer study on uptake and excretion of trace elements in rats. / Yanaga, Makoto; Enomoto, Shuichi; Hirunuma, Rieko; Furuta, Riko; Endo, Kazutoyo; Tanaka, Akira; Ambe, Shizuko; Tozawa, Machiko; Ambe, Fumitoshi.

In: Applied Radiation and Isotopes, Vol. 47, No. 2, 1996, p. 235-240.

Research output: Contribution to journalArticle

Yanaga, M, Enomoto, S, Hirunuma, R, Furuta, R, Endo, K, Tanaka, A, Ambe, S, Tozawa, M & Ambe, F 1996, 'Multitracer study on uptake and excretion of trace elements in rats', Applied Radiation and Isotopes, vol. 47, no. 2, pp. 235-240. https://doi.org/10.1016/0969-8043(95)00279-0
Yanaga, Makoto ; Enomoto, Shuichi ; Hirunuma, Rieko ; Furuta, Riko ; Endo, Kazutoyo ; Tanaka, Akira ; Ambe, Shizuko ; Tozawa, Machiko ; Ambe, Fumitoshi. / Multitracer study on uptake and excretion of trace elements in rats. In: Applied Radiation and Isotopes. 1996 ; Vol. 47, No. 2. pp. 235-240.
@article{497cf4569fc04fd989e9d1cd9fad989b,
title = "Multitracer study on uptake and excretion of trace elements in rats",
abstract = "The multitracer technique was first applied to the investigation of the uptake and excretion behaviour of trace elements in rats. A multitracer solution, prepared by irradiation of a gold target with a 14N-beam from the RIKEN Ring Cyclotron, was orally administered to male Wistar rats. The uptake and excretion rates of 23 elements, Be, Mn, Co, Zn, As, Rb, Sr, Y, Zr, Ce, Pm, Eu, Gd, Tb, Er, Tm, Yb, Lu, Hf, W, Re, Ir and Pt, were simultaneously determined under strictly identical experimental conditions. For some of the elements, the results obtained were consistent with previous reports on uptake and excretion of the elements in animals. For the other elements, unique behaviour was revealed for the first time as described in the present work. These results show that the multitracer technique has excellent reliability and versatility for a comparative study of the uptake and excretion of many different elements in animals.",
author = "Makoto Yanaga and Shuichi Enomoto and Rieko Hirunuma and Riko Furuta and Kazutoyo Endo and Akira Tanaka and Shizuko Ambe and Machiko Tozawa and Fumitoshi Ambe",
year = "1996",
doi = "10.1016/0969-8043(95)00279-0",
language = "English",
volume = "47",
pages = "235--240",
journal = "Applied Radiation and Isotopes",
issn = "0969-8043",
publisher = "Elsevier Limited",
number = "2",

}

TY - JOUR

T1 - Multitracer study on uptake and excretion of trace elements in rats

AU - Yanaga, Makoto

AU - Enomoto, Shuichi

AU - Hirunuma, Rieko

AU - Furuta, Riko

AU - Endo, Kazutoyo

AU - Tanaka, Akira

AU - Ambe, Shizuko

AU - Tozawa, Machiko

AU - Ambe, Fumitoshi

PY - 1996

Y1 - 1996

N2 - The multitracer technique was first applied to the investigation of the uptake and excretion behaviour of trace elements in rats. A multitracer solution, prepared by irradiation of a gold target with a 14N-beam from the RIKEN Ring Cyclotron, was orally administered to male Wistar rats. The uptake and excretion rates of 23 elements, Be, Mn, Co, Zn, As, Rb, Sr, Y, Zr, Ce, Pm, Eu, Gd, Tb, Er, Tm, Yb, Lu, Hf, W, Re, Ir and Pt, were simultaneously determined under strictly identical experimental conditions. For some of the elements, the results obtained were consistent with previous reports on uptake and excretion of the elements in animals. For the other elements, unique behaviour was revealed for the first time as described in the present work. These results show that the multitracer technique has excellent reliability and versatility for a comparative study of the uptake and excretion of many different elements in animals.

AB - The multitracer technique was first applied to the investigation of the uptake and excretion behaviour of trace elements in rats. A multitracer solution, prepared by irradiation of a gold target with a 14N-beam from the RIKEN Ring Cyclotron, was orally administered to male Wistar rats. The uptake and excretion rates of 23 elements, Be, Mn, Co, Zn, As, Rb, Sr, Y, Zr, Ce, Pm, Eu, Gd, Tb, Er, Tm, Yb, Lu, Hf, W, Re, Ir and Pt, were simultaneously determined under strictly identical experimental conditions. For some of the elements, the results obtained were consistent with previous reports on uptake and excretion of the elements in animals. For the other elements, unique behaviour was revealed for the first time as described in the present work. These results show that the multitracer technique has excellent reliability and versatility for a comparative study of the uptake and excretion of many different elements in animals.

UR - http://www.scopus.com/inward/record.url?scp=0029935314&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029935314&partnerID=8YFLogxK

U2 - 10.1016/0969-8043(95)00279-0

DO - 10.1016/0969-8043(95)00279-0

M3 - Article

C2 - 8852630

AN - SCOPUS:0029935314

VL - 47

SP - 235

EP - 240

JO - Applied Radiation and Isotopes

JF - Applied Radiation and Isotopes

SN - 0969-8043

IS - 2

ER -