Multiple liver metetastases of breast cancer: Report of a case successfully treated with hormone-cytokine-chemotherapy

Yoshio Naomoto, Hiroshi Sadamori, Hiroyoshi Matsukawa, Yasuhiro Shirakawa, Tomoki Yamatsuji, Shinya Saito, Norihiko Hino, Hiroshi Isozaki, Norihisa Takakura, Noriaki Tanaka

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


The prognosis of patients with hepatic metastasis from breast cancer is usually extremely poor. We present the case of a 39-year-old Japanese woman diagnosed with multiple liver metastasis from breast cancer. A novel approach consisting of hormone-cytokine-chemotherapy with an arterial infusion therapy was carried out. Computed tomography and ultrasonography revealed that the multiple liver metastases were reduced with remaining calcification. Tumor markers decreased rapidly. Complete regression was achieved after these treatments. To date, there has been no relapse during the 8-year follow-up period. These results suggest that the hormone-cytokine-chemotherapy might be a rational modality of treatment against multiple metastatic breast cancer.

Original languageEnglish
Pages (from-to)390-394
Number of pages5
JournalJapanese journal of clinical oncology
Issue number8
Publication statusPublished - Aug 1999


  • Breast cancer
  • Chemotherapy
  • Cytokine
  • Hormone
  • Liver metastasis
  • Survival

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research


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