Multiple carcinoid tumor combined with mucosal carcinoma in the stomach. A case report.

Tadashi Yoshino, Y. Ohtsuki, Y. Shimada, K. Takahashi, H. Sonobe, K. Hayashi, S. Nakamura, M. Motoi, T. Akagi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A case of gastric multiple carcinoid tumor combined with mucosal carcinoma in a 63-year-old female is reported. The carcinoid tumors, larger than 0.5 mm in diameter, and endocrine cell micronests, smaller than 0.5 mm in diameter, were mostly located in areas of chronic atrophic gastritis. Their distribution was coincident with that of multiple carcinoid tumor in type A gastritis. The majority of the tumor cells were positive for human chorionic gonadotropin (HCG) and Leu 7 by immunohistochemistry and contained various numbers of intracytoplasmic secretory granules as revealed by electron microscopy. Two mucosal carcinoma foci did not show endocrine characteristics. These carcinoid tumors were thought to have originated in HCG-producing argyrophil cells which had been stimulated by hypergastrinemia accompanying chronic atrophic gastritis. The mucosal carcinomas were regarded as incidental.

Original languageEnglish
Pages (from-to)1669-1678
Number of pages10
JournalActa Pathologica Japonica
Volume37
Issue number10
Publication statusPublished - Oct 1987

Fingerprint

Carcinoid Tumor
Stomach
Carcinoma
Atrophic Gastritis
Chorionic Gonadotropin
Endocrine Cells
Secretory Vesicles
Gastritis
Electron Microscopy
Immunohistochemistry
Neoplasms

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Yoshino, T., Ohtsuki, Y., Shimada, Y., Takahashi, K., Sonobe, H., Hayashi, K., ... Akagi, T. (1987). Multiple carcinoid tumor combined with mucosal carcinoma in the stomach. A case report. Acta Pathologica Japonica, 37(10), 1669-1678.

Multiple carcinoid tumor combined with mucosal carcinoma in the stomach. A case report. / Yoshino, Tadashi; Ohtsuki, Y.; Shimada, Y.; Takahashi, K.; Sonobe, H.; Hayashi, K.; Nakamura, S.; Motoi, M.; Akagi, T.

In: Acta Pathologica Japonica, Vol. 37, No. 10, 10.1987, p. 1669-1678.

Research output: Contribution to journalArticle

Yoshino, T, Ohtsuki, Y, Shimada, Y, Takahashi, K, Sonobe, H, Hayashi, K, Nakamura, S, Motoi, M & Akagi, T 1987, 'Multiple carcinoid tumor combined with mucosal carcinoma in the stomach. A case report.', Acta Pathologica Japonica, vol. 37, no. 10, pp. 1669-1678.
Yoshino T, Ohtsuki Y, Shimada Y, Takahashi K, Sonobe H, Hayashi K et al. Multiple carcinoid tumor combined with mucosal carcinoma in the stomach. A case report. Acta Pathologica Japonica. 1987 Oct;37(10):1669-1678.
Yoshino, Tadashi ; Ohtsuki, Y. ; Shimada, Y. ; Takahashi, K. ; Sonobe, H. ; Hayashi, K. ; Nakamura, S. ; Motoi, M. ; Akagi, T. / Multiple carcinoid tumor combined with mucosal carcinoma in the stomach. A case report. In: Acta Pathologica Japonica. 1987 ; Vol. 37, No. 10. pp. 1669-1678.
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